Results 151 to 160 of about 311,587 (357)
Epithelial–Mesenchymal Transition (EMT) : its theranostic role in cancer progression and metastasis [PDF]
, 2014 Epithelial-mesenchymal transition (EMT) is a process by which a fully differentiated epithelial cell attains mesenchymal traits and capabilities such as motility and invasiveness. There are three types.
Baldacchino, Alexandra, Grech, Alfred
core
FEBS Open Bio, EarlyView.We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang +9 more
wiley +1 more source
[Epithelial-mesenchymal transition and tumor metastasis].
Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2011 Metastasis is the transfer of malignant tumors from one organ to a distant organ. It is the most common cause of death in cancer patients. Different molecular mechanisms enable tumor cells to infiltrate the surrounding tissue, invade blood vessels and leave the blood stream at a different site.
Qinghua Zhou, Zhihao Wu, Rongzhi Zhao
openaire +4 more sources
High Activity of Serum Response Factor in the Mesenchymal Transition of Epithelial Tumor Cells Is Regulated by RhoA Signaling [PDF]
, 2002 Eleni Psichari +4 more
openalex +1 more source
FEBS Open Bio, EarlyView.Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee +5 more
wiley +1 more source
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation [PDF]
, 2003 Luika Timmerman +10 more
openalex +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Tumor Necrosis Factor-α Stimulates the Epithelial-to-Mesenchymal Transition of Human Colonic Organoids [PDF]
, 2003 Richard C. Bates, Arthur M. Mercurio
openalex +1 more source
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
Epithelial to Mesenchymal Transition in Human Breast Cancer Can Provide a Nonmalignant Stroma [PDF]
, 2003 Ole W. Petersen +7 more
openalex +1 more source