CDK4/6 and BET inhibitors synergistically suppress pancreatic tumor growth and epithelial-to-mesenchymal transition by regulating the GSK3β-mediated Wnt/β-catenin pathway. [PDF]
Gu J +9 more
europepmc +1 more source
Bioceramics-enhanced patch activates epicardial epithelial-to-mesenchymal transition via Notch pathway for cardiac repair. [PDF]
Ding C +8 more
europepmc +1 more source
The kinase domain of TRPM7 interacts with PAK1 and regulates pancreatic cancer cell epithelial-to-mesenchymal transition. [PDF]
Auwercx J +15 more
europepmc +1 more source
Correction to "MicroRNA-1275 induces radiosensitization in oesophageal cancer by regulating epithelial-to-mesenchymal transition via Wnt/β-catenin pathway". [PDF]
europepmc +1 more source
Related searches:
Epithelial–mesenchymal transition (EMT) is a key step in transdifferentiation process in solid cancer development. Forthcoming evidence suggest that the stratified program transforms polarized, immotile epithelial cells to migratory mesenchymal cells ...
Vishal Das +4 more
semanticscholar +1 more source
Mesenchymal to epithelial transition in sarcomas
European Journal of Cancer, 2014Mesenchymal to epithelial transition (MET) in carcinomas has been proposed to promote the growth of epithelial tumour cells at distant sites during metastasis. MET has also been suggested as an important biological and clinical process in mesenchymal tumors, sarcomas.
Jilong Yang +9 more
openaire +2 more sources
Polyamines modulate epithelial-to-mesenchymal transition
Amino Acids, 2011Epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition are biologic processes responsible for conversion of epithelial cells into a mesenchymal phenotype or viceversa, respectively. They occur during embryo- and foetal-development and, in adult organisms, are involved in wound healing, in the genesis and progression of organ ...
Alessandra, Compagnone +13 more
openaire +3 more sources
Mnt Represses Epithelial Identity To Promote Epithelial-to-Mesenchymal Transition
Molecular and Cellular Biology, 2021The multistep process of epithelial-to-mesenchymal transition (EMT), whereby static epithelial cells become migratory mesenchymal cells, plays a critical role during various developmental contexts, wound healing, and pathological conditions such as cancer metastasis.
Deborah P. Lavin +3 more
openaire +3 more sources
Epithelial-to-mesenchymal transition in tumor progression
Medical Oncology, 2017The epithelial-to-mesenchymal transition (EMT) is a biological process in which a non-motile epithelial cell changes to a mesenchymal state with invasive capacities. However, the EMT program is involved in both physiological and pathological processes.
Elena Prieto-García +3 more
semanticscholar +3 more sources
Epigenetic Regulation of Epithelial to Mesenchymal Transition
Current Cancer Drug Targets, 2013Epithelial-mesenchymal transition (EMT) is a vital process implemented in embryo development, organ fibrosis, and cancer metastasis. Several transcription factors and signaling pathways impinge on the transcriptional program of the cell, leading to the change of cell phenotype without alteration of genotype.
Peiwei, Huangyang, Yongfeng, Shang
openaire +2 more sources

