Results 211 to 220 of about 244,147 (243)

The kinase domain of TRPM7 interacts with PAK1 and regulates pancreatic cancer cell epithelial-to-mesenchymal transition. [PDF]

open access: yesCell Death Dis
Auwercx J   +15 more
europepmc   +1 more source
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The basics of epithelial–mesenchymal transition (EMT): A study from a structure, dynamics, and functional perspective

Journal of Cellular Physiology, 2019
Epithelial–mesenchymal transition (EMT) is a key step in transdifferentiation process in solid cancer development. Forthcoming evidence suggest that the stratified program transforms polarized, immotile epithelial cells to migratory mesenchymal cells ...
Vishal Das   +4 more
semanticscholar   +1 more source

Mesenchymal to epithelial transition in sarcomas

European Journal of Cancer, 2014
Mesenchymal to epithelial transition (MET) in carcinomas has been proposed to promote the growth of epithelial tumour cells at distant sites during metastasis. MET has also been suggested as an important biological and clinical process in mesenchymal tumors, sarcomas.
Jilong Yang   +9 more
openaire   +2 more sources

Polyamines modulate epithelial-to-mesenchymal transition

Amino Acids, 2011
Epithelial-to-mesenchymal transition and mesenchymal-to-epithelial transition are biologic processes responsible for conversion of epithelial cells into a mesenchymal phenotype or viceversa, respectively. They occur during embryo- and foetal-development and, in adult organisms, are involved in wound healing, in the genesis and progression of organ ...
Alessandra, Compagnone   +13 more
openaire   +3 more sources

Mnt Represses Epithelial Identity To Promote Epithelial-to-Mesenchymal Transition

Molecular and Cellular Biology, 2021
The multistep process of epithelial-to-mesenchymal transition (EMT), whereby static epithelial cells become migratory mesenchymal cells, plays a critical role during various developmental contexts, wound healing, and pathological conditions such as cancer metastasis.
Deborah P. Lavin   +3 more
openaire   +3 more sources

Epithelial-to-mesenchymal transition in tumor progression

Medical Oncology, 2017
The epithelial-to-mesenchymal transition (EMT) is a biological process in which a non-motile epithelial cell changes to a mesenchymal state with invasive capacities. However, the EMT program is involved in both physiological and pathological processes.
Elena Prieto-García   +3 more
semanticscholar   +3 more sources

Epigenetic Regulation of Epithelial to Mesenchymal Transition

Current Cancer Drug Targets, 2013
Epithelial-mesenchymal transition (EMT) is a vital process implemented in embryo development, organ fibrosis, and cancer metastasis. Several transcription factors and signaling pathways impinge on the transcriptional program of the cell, leading to the change of cell phenotype without alteration of genotype.
Peiwei, Huangyang, Yongfeng, Shang
openaire   +2 more sources

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