Results 31 to 40 of about 36,944 (259)

WWTR1(TAZ)-CAMTA1 reprograms endothelial cells to drive epithelioid hemangioendothelioma

open access: yesGenes & Development, 2021
In this study, Driskill et al. studied whether the TAZ-CAMTA1 gene fusion is a driver of epithelioid hemangioendothelioma (EHE), a poorly understood and devastating vascular cancer.
Jordan H. Driskill   +7 more
semanticscholar   +1 more source

The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma

open access: yesClinical Cancer Research, 2022
Purpose: A consistent genetic alteration in vascular cancer epithelioid hemangioendothelioma (EHE) is the t(1;3)(p36;q25) chromosomal translocation, which generates a WWTR1(TAZ)-CAMTA1 (TC) fusion gene. TC is a transcriptional coactivator that drives EHE.
Shuang Ma   +9 more
semanticscholar   +1 more source

Hepatic epithelioid hemangioendothelioma: Clinical characteristics, diagnosis, treatment, and prognosis

open access: yesWorld Journal of Clinical Cases, 2022
BACKGROUND Hepatic epithelioid hemangioendothelioma (HEHE) is a rare hepatic vascular tumor with unpredictable malignant potential. The etiology, characteristics, diagnosis, treatment, and prognosis of HEHE are not well-understood, and large-scale ...
Man Zhao, Fei Yin
semanticscholar   +1 more source

MRI appearances of hepatic epithelioid hemangioendothelioma: a retrospective study of 57 patients

open access: yesInsights into Imaging, 2022
Background Hepatic epithelioid hemangioendothelioma (HEH) is extremely rare and the MRI features have never been investigated in a large group of patients. Methods A retrospective study was designed to review the MRI images of HEH patients.
Xiaolei Liu   +7 more
semanticscholar   +1 more source

Unraveling the Biology of Epithelioid Hemangioendothelioma, a TAZ–CAMTA1 Fusion Driven Sarcoma

open access: yesCancers, 2022
Simple Summary Epithelioid hemangioendothelioma (EHE) is a rare vascular cancer that involves a gain-of-function gene fusion involving TAZ, a transcriptional coactivator, and one of two end effectors of the Hippo pathway. Although the activity of TAZ and/
C. Seavey, A. Pobbati, B. Rubin
semanticscholar   +1 more source

A review of hepatic epithelioid hemangioendothelioma—Analyzing patient characteristics and treatment strategies

open access: yesJournal of Surgical Oncology, 2022
Hepatic epithelioid hemangioendothelioma (HEH) is a rare vascular tumor of unknown etiology and unpredictable natural history. To date, no large‐scale studies have been published evaluating this disease due to its rare occurrence.
P. Ajay   +10 more
semanticscholar   +1 more source

The challenging surgical management of hepatic epithelioid hemangioendothelioma: a narrative review.

open access: yesChinese Clinical Oncology, 2022
BACKGROUND AND OBJECTIVE Hepatic epithelioid hemangioendothelioma (HEHE) is an uncommon vascular endothelial cell cancer involving the hepatic tissue with full malignant potential.
F. Giovanardi   +4 more
semanticscholar   +1 more source

A Case Report of Prostatic and Peritoneal Hemangioendothelioma

open access: yesJournal of Urological Surgery, 2018
Epithelioid hemangioendothelioma is a rare endothelial neoplasm that is uncommonly described in the urinary system. To date, only one case has been described as originating from the prostate.
Michael Lao   +3 more
doaj   +1 more source

Pseudomyogenic Hemangioendothelioma (Epithelioid Sarcoma-Like Hemangioendothelioma) [PDF]

open access: yesArchives of Pathology & Laboratory Medicine, 2019
Pseudomyogenic hemangioendothelioma (PMH) is a rare vascular tumor that presents more frequently in young adults and has a male predominance. It is usually located in the superficial or deep soft tissues of the extremities, but concurrent bone involvement can be present.
Gustavo A, Caballero, Pablo D, Roitman
openaire   +2 more sources

Sirolimus combined with interferon-alpha 2b therapy for giant hepatic epithelioid hemangioendothelioma: a case report

open access: yesFrontiers in Oncology, 2022
Hepatic epithelioid hemangioendothelioma (HEH) is a very rare tumor originated from vascular endothelial cells, with unpredictable malignancy. No standard treatment has been established yet. Although surgical resection and liver transplantation have been
Xiaolei Liu   +6 more
semanticscholar   +1 more source

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