Results 51 to 60 of about 409 (135)

Tibial epithelioid hemangioendothelioma

Human Pathology: Case Reports, 2020
Epithelioid hemangioendotheliomas (EHE) represent less than 1% of all bone tumors. They often present in the long tubular bones or in the axial skeleton, but are often multifocal in nature and can present in the liver and lung. This paper presents a case
Eugene Kim, Ronald Williams, Amanda Rivera-Begeman   +2 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, Volume 20, Issue 2, Page 493-510, February 2026.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Open surgical treatment for rare epithelioid hemangioendothelioma of the common femoral vein

Journal of Interventional Medicine, 2019
Epithelioid hemangioendothelioma is a very rare disease affecting big blood vessels, especially veins. There have been very few articles describing the disease.
Xiangjiang Guo, Shuo fei Yang, Guan hua Xue, Jia quan Chen, Hao Zhang, Lan Zhang   +5 more
doaj   +1 more source

Real‐World Experience of Efficacy and Tolerability of Continuous Infusion Ifosfamide for Advanced Soft Tissue and Bone Sarcoma Patients: A Single Centre Retrospective Cohort

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background In the absence of randomized trials, selecting second or later‐line therapies in advanced sarcoma generally hinges on histology, patient performance status, and toxicity profile. We herein report a real‐world sarcoma referral center experience on continuous infusion Ifosfamide (ciIFO), in advanced Soft tissue sarcomas (STS) and bone
Ilaria Mascagni, Alice Laffi, Maria Susanna Grimaudo, Ferdinando Carlo Maria Cananzi, Laura Samà, Salvatore Lorenzo Renne, Federico D’Orazio, Pierina Navarria, Elena Clerici, Carlo Carnaghi, Sara Farinatti, Erika Stucchi, Marialudovica Le Moli, Laura Giordano, Robert G. Maki, Armando Santoro, Alexia Francesca Bertuzzi   +16 more
wiley   +1 more source

Dual immunotherapy alternating with anti-PD-1 antibody plus liposomal doxorubicin show good efficacy in prostate epithelioid hemangioendothelioma: a case report

Frontiers in Immunology
Epithelioid hemangioendothelioma is a rare vascular malignancy, and currently, there is no standard treatment regimen for this disease and existing treatment options have limited efficacy.
Jie Zhang, Jie Zhang, Qin Ye, Xudan Yang, Tenglong Li, Shan Huang, Ping Zhou, Yumei Feng, Hao Liu, Ke Xie   +9 more
doaj   +1 more source

ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju, Tao Zhang, Jianchen Cui, Yulim Lee, Suho Lee, Ho Min Kim, Boohwi Hong, Jiho Park, Chul Hee Choi, Hyon‐Seung Yi, Jun Young Heo, Woosuk Chung   +11 more
wiley   +1 more source

Single‐nucleus RNA sequencing reveals the distinct heterogeneity of primary pulmonary sarcomas (PPS) and pulmonary sarcomatoid carcinoma (PSC)

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Single‐nucleus RNA sequencing (snRNA‐seq) maps the cellular diversity of pulmonary sarcomatoid carcinoma (PSC) and primary pulmonary sarcomas (PPS). AT2 cells, a major source of epithelial cells in PSC, underwent malignant transformation primarily through epithelial–mesenchymal transition, suggesting AT2 cells may serve as the origin of PSC.
Jianfei Zhu, Yanlu Xiong, Shouzheng Ma, Jun Wei, Jiakuan Chen, Wenchen Wang, Qianqian Duan, Qin Zhang, Dongsheng Chen, Wanglong Deng, Tao Jiang, Jie Lei   +11 more
wiley   +1 more source

A Tragical Paediatric Case History of Intraorbital and Intracranial Epithelioid Hemangioendothelioma

Case Reports in Neurological Medicine, 2012
Epithelioid hemangioendothelioma (EHE) is a rare tumor of intermediate malignancy. We report a case of intracranial and intraorbitar EHE. A 3-year-old girl presented with a 3-month history of progressive left exophthalmia.
K. Aniba, M. Laghmari, M. Lmejjati, H. Ghannane, S. Ait Benali   +4 more
doaj   +1 more source

Comparative Analysis of a Dual DNA–RNA Panel and a DNA‐Only Panel for Sarcoma: Real‐World Data From a Nationwide Genomic Database

Cancer Science, Volume 117, Issue 1, Page 156-168, January 2026.
Dual DNA–RNA panel with matched tumor–normal testing may improve diagnostic accuracy and inform treatment decisions in the routine clinical management of sarcoma. ABSTRACT Next‐generation sequencing‐based comprehensive cancer genomic profiling is promising in cancer management; however, most studies rely on tumor‐only DNA panels from single ...
Eiji Nakata, Kiichiro Ninomiya, Tatsunori Osone, Daisuke Ennishi, Shuta Tomida, Tomohiro Fujiwara, Toshiyuki Kunisada, Mashu Futagawa, Akira Hirasawa, Shinichi Toyooka, Toshifumi Ozaki   +10 more
wiley   +1 more source

A Rare Case of Neonatal Kaposiform Hemangioendothelioma With Kasabach–Merritt Phenomenon Presenting as an Abdominal Mass Without Cutaneous Manifestations

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm that typically presents in infancy or early childhood, classified as a locally aggressive/borderline vascular tumor. It most commonly involves superficial and deep soft tissues, often demonstrating infiltrative growth into adjacent muscle and bone, whereas retroperitoneal or ...
Su Young Park, Amrryn Halari, Jessenia Palacio-Meadows, Nehal S. Parikh, Danielle Bentsen, Surasak Puvabanditsin, Kalyani Sen   +6 more
wiley   +1 more source