Results 91 to 100 of about 258,245 (301)

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

open access: yesHealth Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha   +2 more
wiley   +1 more source

Stem cell-based therapeutic strategies for corneal epithelium regeneration

open access: yes, 2021
Any significant loss of vision or blindness caused by corneal damages is referred to as corneal blindness. Corneal blindness is the fourth most common cause of blindness worldwide, representing more than 5 of the total blind population.
Banitalebi-Dehkordi, Mehdi   +6 more
core   +1 more source

Diurnal variation of corneal epithelium and stroma measured by optical coherence tomography

open access: yesThe Pan-American Journal of Ophthalmology
Purpose: The purpose of the study is to evaluate whether there is a significant diurnal variation in the thickness of corneal epithelium and stroma, in healthy volunteers, using corneal optical coherence tomography (OCT).
Rodrigo Caporrino Moreira   +3 more
doaj   +1 more source

Transient receptor potential cation channel subfamily V member 1 expressing corneal sensory neurons can be subdivided into at least three subpopulations

open access: yesFrontiers in Neuroanatomy, 2015
The cornea is innervated by 3 main functional classes of sensory neurons: polymodal nociceptors, pure mechano-nociceptors and cold-sensing neurons. Here we explored transient receptor potential cation channel subfamily V member 1 (TRPV1) expression in ...
Abdulhakeem eAlamri   +3 more
doaj   +1 more source

The Effect of Resveratrol on Protecting Corneal Epithelial Cells from Cytotoxicity Caused by Moxifloxacin and Benzalkonium Chloride

open access: yes, 2017
PURPOSE. Moxifloxacin (MOX), a fourth generation fluoroquinolone (FQ), has a wide antibacterial spectrum, but may show cytotoxicity characterized by high productions of reactive oxygen species (ROS).
陳達慶;蔡紫薰;胡芳蓉;陳瑞華;王一中;蘇銘嘉   +1 more
core   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu   +4 more
wiley   +1 more source

Pharmaceutical aspect of corneal injury

open access: yes, 2021
Corneal injury can be minor and sever.corneal trauma can be corneal abrasion,corneal perforation,corneal foreign body.different tdrugs can be consider for tratement of patiente to relive pain and reduce inflammation.
Sohrabi, Reyhaneh
core  

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Hemoglobin Expression and Function in Human Corneal Epithelium [PDF]

open access: yes, 2019
The corneal epithelium forms the outer layer of the cornea. It provides mechanical protection, prevents fluid loss and forms a barrier to invasive pathogens.
Perez, Erin   +3 more
core   +4 more sources

Invisible shield: Review of the corneal epithelium as a barrier to UV radiation, pathogens, and other environmental stimuli

open access: yesJournal of Ophthalmic & Vision Research, 2017
The ocular surface is comprised of the cornea and conjunctiva, which are structures that not only protect the eye but also enable vision. The corneal epithelium is the most superficial layer of the cornea, and therefore first line of defense against ...
Hasan Bashir, John T Seykora, Vivian Lee
doaj   +1 more source

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