This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang +6 more
wiley +1 more source
Diagnostic Role of Anterior Segment Optical Coherence Tomography in an Atypical Presentation of Varicella Zoster Virus Interstitial Keratitis: A Case Report. [PDF]
Alsaggaf K, Jomar DE, Al-Swailem SA.
europepmc +1 more source
Development and Validation of an In Vitro Ocular Irritation Test for Ophthalmic Medical Devices with a Novel Reconstructed Human Corneal Epithelium Model. [PDF]
Rawat P +7 more
europepmc +1 more source
The technical and practical implementation of fundus photography in equids
Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley +1 more source
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki +4 more
wiley +1 more source
The Lid Wiper Effect on Corneal Epithelial Thickness Pattern in Healthy Eyes as Characterized by Zernike Analysis. [PDF]
Yazbeck H +4 more
europepmc +1 more source
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Post-Orthokeratology Changes in the Corneal Epithelium Induced by an Orthokeratology Lens: An Anterior-Segment Optical Coherence Tomography Assessment. [PDF]
Nemoto K, Kamiya K, Hata S, Kobayashi M.
europepmc +1 more source
ZEB1 Modifies VE‐Cadherin Signaling in Lymphatic Endothelial Cells
ABSTRACT Objective Zinc finger E‐box‐binding homeobox 1 (ZEB1) is a transcription factor primarily known for its regulatory roles in epithelial‐to‐mesenchymal transition (EMT) and cell fate determination. Recent studies suggest that endothelial ZEB1 signaling promotes blood vessel growth and reduces junctional integrity, although the underlying ...
Nada S. Ahmed +17 more
wiley +1 more source
Therapeutic effects of Ghrita Manda Ashchyotana on tear film stability, corneal integrity, and IL-6 expression in a benzalkonium chloride-induced murine dry eye model. [PDF]
Janardhanan RS +2 more
europepmc +1 more source

