Blue Light Pollution and Ocular Surface Toxicity: p53-Mediated Ferroptosis in Corneal Epithelium Drives Dry Eye Pathogenesis. [PDF]
Zhang L +5 more
europepmc +1 more source
PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang +13 more
wiley +1 more source
SPARC Promotes Corneal Epithelial Wound Healing Through β-catenin Nuclear Translocation and c-Met Activation. [PDF]
Zhang M +8 more
europepmc +1 more source
Inositol pyrophosphate kinases in health and disease
In mammalian cells, IP6Ks and PPIP5Ks are the key kinases synthesizing the inositol pyrophosphates 5PP‐InsP5 and InsP8. They are essential for early development but also mediate age‐related diseases, including metabolic disorders, cardiovascular diseases, neurodegenerative diseases, and cancers.
Changchang Xing +6 more
wiley +1 more source
Spontaneous Superficial Ulcerative Keratitis in Client-Owned Cats: Risk Factors for Delayed Healing, Corneal Sequestration, or Corneal Stromal Vascularization. [PDF]
Reynolds BD +7 more
europepmc +1 more source
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim +6 more
wiley +1 more source
Conservative Management of Intrastromal Corneal Ring Segment Extrusion Using Suture-Assisted Repositioning: A Case Series. [PDF]
Warrak J +3 more
europepmc +1 more source
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître +7 more
wiley +1 more source
Dopamine receptors in ocular surface biology: Current evidence and future directions. [PDF]
Shetty R +6 more
europepmc +1 more source
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le +4 more
wiley +1 more source

