Acute corneal edema without epithelium compromise. A case report and literature review [PDF]
Acute corneal edema is caused by various factors, with different levels of severity, and various forms of presentation. This paper reports the case of a male patient presenting with acute corneal edema without epithelium compromise, whose clinical ...
José Augusto Urrego-Díaz +3 more
doaj +2 more sources
Masamichi Fukuda1, Hiroshi Sasaki11Department of Ophthalmology, Kanazawa Medical University, Uchinada, JapanPurpose: We attempted to develop a device for measuring electrical corneal resistance (CR) using corneal contact lens electrodes to quantitatively
Fukuda M, Sasaki H
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Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial Homeostasis [PDF]
Background: Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6(+/-) heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal ...
Fullwood, Nigel J. +34 more
core +5 more sources
Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis
Corneal epithelium shares similar molecular signatures to other stratified epithelia. Here, the authors map super-enhancers and accessible chromatin in corneal epithelium, identifying a transcription regulatory circuit, including RUNX1, PAX6, and SMAD3 ...
Mingsen Li +18 more
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Summary: Existing flow cytometry approaches identify immune cells using the whole infected/inflamed cornea, which limits its ability to distinguish the immune cells infiltrating the corneal epithelium from the corneal stroma.
Mizumi Setia +2 more
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Comparison of corneal biological parameters between transepithelial and epithelium-off corneal cross-linking in keratoconus [PDF]
AIM: To evaluate the differences in corneal biological parameters between transepithelial and epithelium-off corneal cross-linking in keratoconus.
Bo-Wen Ouyang +6 more
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COMPARATIVE STUDY BETWEEN EPITHELIUM ON AND EPITHELIUM OFF COLLAGEN CROSS LINKING WITH RIBOFLAVIN AND UVR IN TREATMENT OF EARLY KERATOCONUS [PDF]
Objective: To compare the safety and efficacy epithelium on versus epithelium off collagen crosslinking with riboflavin and UVR in treatment of early keratoconus. Patients and Methods: Thepresent study was a prospective, randomized study. 40 eyes from 25
Youssef, H. +2 more
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Mechanobiology of the corneal epithelium
There has been a drive to develop new cell based therapies to treat corneal blindness, one of the most common causes of blindness worldwide. Mechanical and physical cues are known to regulate the behavior of many cell types, however studies examining these effects on corneal epithelial cells have been limited in number and their findings have not ...
Masterton, Sophia, Ahearne, Mark
openaire +4 more sources
Low‐intensity low‐frequency ultrasound mediates riboflavin delivery during corneal crosslinking
We employed the mechanical effect from 40 kHz ultrasound (US) to improve the delivery of riboflavin into corneal stroma for collagen crosslinking, which can benefit the treatment of keratoconus and other corneal ectasias.
Zhe Sun +5 more
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Real-time polymerase chain reaction for the diagnosis of necrotizing herpes stromal keratitis [PDF]
AIM: To design, optimize and validate a rapid, internally controlled real-time polymerase chain reaction (RT-PCR) test for herpes simplex virus (HSV) in the diagnosis of necrotizing herpes stromal keratitis. METHODS: Tears alone or together with corneal
Jun-Xin Ma, Lin-Nong Wang, Ru-Xia Zhou
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