Results 21 to 30 of about 258,245 (301)

The core planar cell polarity gene, Vangl2, directs adult corneal epithelial cell alignment and migration [PDF]

Royal Society Open Science, 2016
This study shows that the core planar cell polarity (PCP) genes direct the aligned cell migration in the adult corneal epithelium, a stratified squamous epithelium on the outer surface of the vertebrate eye.
Amy S. Findlay, D. Alessio Panzica, Petr Walczysko, Amy B. Holt, Deborah J. Henderson, John D. West, Ann M. Rajnicek, J. Martin Collinson   +7 more
doaj   +1 more source

Epithelium-off corneal cross-linking versus transepithelial diluted alcohol and iontophoresis-assisted corneal cross-linking in keratoconus patients with thin corneas

, 2022
Aims:To evaluate the efficacy and safety of transepithelial diluted alcohol and iontophoresis-assisted corneal cross-linking (DAI-CXL) and compare 24-month visual and topographic outcomes with accelerated CXL using hypo-osmolar riboflavin (A-CXL) in ...
Uysal, Betül Seher, Murat Yüksel, Betül Seher Uysal, Mehmet Cüneyt Özmen, Yüksel, Murat, Özmen, Mehmet Cüneyt, Kamil Bilgihan, Aydın, Bahri, Bahri Aydın, Bilgihan, Mustafa Kamil   +9 more
core   +1 more source

Topical rosiglitazone is an effective anti-scarring agent in the cornea [PDF]

, 2013
Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome ...
Phipps, Richard P., Holly B Hindman, MacRae, Scott, Patricia J Sime, Krystel R Huxlin, David Ciufo, Jeon, Kye-Im, Richard P Phipps, Sime, Patricia J., DeMagistris, Margaret, Ciufo, David, Huxlin, Krystel R., Jens Bühren, Scott MacRae, Kye-Im Jeon, Margaret DeMagistris, Bühren, Jens, Hindman, Holly B.   +17 more
core   +2 more sources

Oxidative stress induces dysregulated autophagy in corneal epithelium of keratoconus patients. [PDF]

PLoS ONE, 2017
Oxidative stress is one of the key factors that contributes to the pathogenesis of keratoconus (KC). Macroautophagy is a vital cellular mechanism that is activated in response to oxidative stress.
Rohit Shetty, Anupam Sharma, Natasha Pahuja, Priyanka Chevour, Neeraja Padmajan, Kamesh Dhamodaran, Chaitra Jayadev, Rudy M M A Nuijts, Arkasubhra Ghosh, Jeyabalan Nallathambi   +9 more
doaj   +1 more source

Corneal epithelial thickness analysis of forme fruste keratoconus with optical coherence tomography [PDF]

International Journal of Ophthalmology, 2021
AIM: To explore the significance of corneal epithelial thickness analysis in diagnosing early keratoconus. METHODS: There were 26 clinical keratoconus, 21 forme fruste keratoconus, 40 high corneal astigmatism (ΔK) and 40 low ΔK eyes involved in the study.
Xiao-Long Yang, Yun Wang, Bao-Gen Luo, Yue Xu, Xiao-Feng Zhang   +4 more
doaj   +1 more source

Eccentric lamellar keratolimbal grafts harvested with a manually guided microkeratome [PDF]

, 2007
Background: To perform lamellar keratolimbal allograft transplantation in a one- step procedure with a single graft, we investigated the feasibility of harvesting eccentric lamellar keratolimbal grafts from conventionally processed corneoscleral buttons ...
Priglinger, Siegfried G., Lackerbauer, Carlo, Grueterich, Martin, Welge-Luessen, Ulrich, Kampik, Anselm, Kenyon, Kenneth R.   +5 more
core   +1 more source

Deciphering the mechanoresponsive role of β-catenin in keratoconus epithelium

Scientific Reports, 2020
Keratoconus (KC) is a corneal dystrophy characterized by progressive ectasia that leads to severe visual impairment and remains one of the leading indications for corneal transplantation. The etiology is believed to be multifactorial and alterations have
Chatterjee Amit, Prema Padmanabhan, Janakiraman Narayanan   +2 more
doaj   +1 more source

A comparative study between epithelium-on and epithelium-off collagen cross-linking with riboflavin and ultraviolet radiation in the treatment of early keratoconus

Journal of the Egyptian Ophthalmological Society, 2016
Purpose We aimed to carry out a comparative study between epithelium-on and epithelium-off collagen cross-linking (CXL) in the treatment of early keratoconus. Patients and methods The present study was a prospective, randomized study. We included 40 eyes
Hassan S Yousef
doaj   +1 more source

Experience of Using Corneal Epithelium Protector Gel for the Treatment of Corneal Erosion for a Patient after Radial Keratotomy

Oftalʹmologiâ, 2022
Currently, one of the actual problems of pharmacotherapy is the treatment of recurrent corneal erosions. Traumatic and postoperative damage to the cornea can disrupt the connection between the basement membrane and the epithelium.
A. S. Semakina
doaj   +1 more source

Investigation of mitophagy biomarkers in corneal epithelium of keratoconus patients [PDF]

, 2022
Purpose: The pathological mechanisms of keratoconus (KC) have not been elucidated yet. Mitophagy is an important mechanism that eliminates damaged mitochondria under oxidative stress, and it could be one of the leading pathological causes of KC.
Yıldız, E, Kuşan, E, İlhan Saraç, Ö, Aydemir, D, Gümüş, K, Şahin, A, Çağıl, N, Karslıoğlu, Mz, Zibandeh, N   +8 more
core   +2 more sources