A new three-dimensional model to describe human corneal oxygenation during contact lenses wear. [PDF]
Gozálvez-Zafrilla JM+2 more
europepmc +1 more source
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi+11 more
wiley +1 more source
Gene proteins, growth factors/their receptors in the wall of chronic calculous cholecystitis-affected gallbladder children. [PDF]
Derbeneva D, Pilmane M, Petersons A.
europepmc +1 more source
Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco+12 more
wiley +1 more source
SLC6A6-Mediated Taurine Uptake Sustains Corneal Epithelial Stem/Progenitor Cell Function to Counteract Age-Related Dysfunction. [PDF]
Li Y+9 more
europepmc +1 more source
Matrix Tropism Influences Endometriotic Cell Attachment Patterns
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault+7 more
wiley +1 more source
The Impact of Epithelial Inflammation in Membrane Remnants on the Outcome of Tympanoplasty. [PDF]
Galindo-Tapia MF+9 more
europepmc +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
Granular Cell Ameloblastomatous Transformation From the Remnants of a Dentigerous Cyst: A Unique Case Report. [PDF]
Hebbale M, Rao P, Halli R, Deo P.
europepmc +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
wiley +1 more source