Results 251 to 260 of about 1,228,539 (340)

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Age- and sex-dependent morphological alterations of rectal mucosa-associated lymphoid tissue in chickens (Gallus gallus domesticus). [PDF]

Poult Sci
Rubel MZU, Namba T, Hiraishi M, Oe S, Ichii O.   +4 more
europepmc   +1 more source

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Proceedings of the National Academy of Sciences of the United States of America, 1992
C. T. Guy, M. Webster, Michael Schaller, T. J. Parsons, R. Cardiff, W. Muller   +5 more
semanticscholar   +1 more source

THE FUNCTION OF THE GOLGI COMPLEX IN TRANSITIONAL EPITHELIUM [PDF]

, 1966
R M Hicks
openalex   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

PROS1 released by lung basal cells limits inflammation in epithelial and monocytes during SARS-CoV-2 infection. [PDF]

Discov Immunol
Simakou T, Szemiel AM, MacDonald L, Kerr K, Somma D, Diallo K, Frew J, Hardy OM, Doohan M, Elmesmari A, McSharry C, Alivernini S, Otto TD, Patel AH, Kurowska-Stolarska M.   +14 more
europepmc   +1 more source

Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

Mucosal Immunology, 2013
N. Mabbott, D. S. Donaldson, H. Ohno, I. Williams, A. Mahajan   +4 more
semanticscholar   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Evaluation of Leak Sites in Central Serous Chorioretinopathy and the Effects of PDT on RPE by Polarization-Sensitive OCT. [PDF]

Transl Vis Sci Technol
Terao R, Saeki Y, Yashiro K, Ota M, Aoki S, Kitamoto K, Azuma K.   +6 more
europepmc   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source