Results 311 to 320 of about 911,928 (364)

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

Establishment of a novel mouse model of colorectal cancer by orthotopic transplantation. [PDF]

BMC Cancer
Chen C, Fu Q, Wang L, Tanaka S, Imajo M.
europepmc   +1 more source

Hydrogel‐Impregnated Robust Interlocking Nano Connector (HiRINC) for Noninvasive Anti‐Migration of Esophageal Stent

Advanced Materials, EarlyView.
The development of hydrogel‐impregnated robust interlocking nano connector (HiRINC) aims to address stent migration by improving tissue adhesion and reducing mechanical mismatch in self‐expandable metallic stents (SEMSs). The network‐like porous layer of HiRINC enhances adhesion and energy dissipation, demonstrates through ex vivo and in vivo tests ...
Eunyoung Jeon, Song Hee Kim, Sukyoung Kim, Dae Sung Ryu, Ji Won Kim, Kayoung Kim, Do Hoon Kim, Jung‐Hoon Park, Joonseok Lee   +8 more
wiley   +1 more source

Drug-free hyaluronic acid-microneedle with unexpected inhibition activity on benzalkonium chloride-induced corneal inflammation and stromal scarring. [PDF]

Mater Today Bio
Huang B, Zeng R, Liu X, Pan L, Bai H, Liao J, Xu W, Fu H, Nan K, Lin S.   +9 more
europepmc   +1 more source

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium. [PDF]

Elife
Medina-Feliciano JG, Valentín-Tirado G, Luna-Martínez K, Beltran-Rivera A, Miranda-Negrón Y, Garcia-Arraras JE.   +5 more
europepmc   +1 more source

Advancements in Carbon‐Based Piezoelectric Materials: Mechanism, Classification, and Applications in Energy Science

Advanced Materials, EarlyView.
Carbon‐based piezoelectric materials are systematically categorized based on their structural and functional properties. The mechanisms of stress‐induced charge transfer are elucidated, and their applications are explored across three key domains: piezoelectric catalysis for energy conversion and environmental remediation, piezoelectric biomedical ...
Mude Zhu, Qingyou Liu, Wai‐Yeung Wong, Linli Xu   +3 more
wiley   +1 more source

HIV-associated penile anaerobes disrupt epithelial barrier integrity. [PDF]

PLoS Pathog
Buchanan LB, Shao Z, Galiwango RM, Constable S, Zuanazzi D, Biribawa VM, Ssemunywa HR, Namuniina A, Okech B, Edfeldt G, Tjernlund A, Tobian AAR, Park DE, Pham T, Aziz M, Salazar JE, Nelson S, Liu CM, Kaul R, Prodger JL.   +19 more
europepmc   +1 more source

Intravasation‐On‐µDevice (INVADE): Engineering Dynamic Vascular Interfaces to Study Cancer Cell Intravasation

Advanced Materials, EarlyView.
Cancer metastasis begins with intravasation, a complex process involving cancer‐endothelial interactions. INVADE (Intravasation‐on‐µDevice), a biomimetic microfluidic platform enables high‐throughput analysis of intravasation under controlled conditions.
Fengtao Jiang, Yingqi Zhang, Guocheng Fang, Yao Wang, Alexander Dupuy, Jasmine Jin, Yi Shen, Khoon S Lim, Yinyan Wang, Yu Shrike Zhang, Ann‐Na Cho, Hongxu Lu, Lining Arnold Ju   +12 more
wiley   +1 more source

Erratum in: Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen. [PDF]

Invest Ophthalmol Vis Sci
europepmc   +1 more source