Results 61 to 70 of about 985,722 (341)
Interplay of GTPases and Cytoskeleton in Cellular Barrier Defects during Gut Inflammation
Frontiers in Immunology, 2017 An essential role of the intestine is to build and maintain a barrier preventing the luminal gut microbiota from invading the host. This involves two coordinated physical and immunological barriers formed by single layers of intestinal epithelial and ...
Rocío López-Posadas +4 more
doaj +1 more source
The Epithelial-Immune Crosstalk in Pulmonary Fibrosis
Frontiers in Immunology, 2021 Interactions between the lung epithelium and the immune system involve a tight regulation to prevent inappropriate reactions and have been connected to several pulmonary diseases.
Thomas Planté-Bordeneuve +4 more
doaj +1 more source
Intestinal macromolecular transport supporting adaptive immunity [PDF]
, 2019 The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
core +2 more sources
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases
Frontiers in Cell and Developmental Biology, 2020 Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the ...
Anu Laulajainen-Hongisto +5 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Regulation of interleukin 33/ST2 signaling of human corneal epithelium in allergic diseases
International Journal of Ophthalmology, 2013 AIM: To identify the function of ST2 and explore the role of IL-33/ST2 signaling in regulating the pro-allergic cytokine production in human corneal epithelial cells (HCECs).METHODS: Human corneal tissues and cultured primary HCECs were treated with IL ...
Jing Lin
doaj +1 more source
On a model mechanism for the spatial patterning of teeth primordia in the Alligator [PDF]
, 1996 We propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator,Alligator mississippiensis. Detailed embryological studies by Westergaard & Ferguson (1986, 1987, 1990) show that jaw growth plays a crucial role ...
Cruywagen, G. C. +6 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Upgrading In Vitro Digestion Protocols with Absorption Models
Applied SciencesIntestinal digestion and absorption are complex processes; thus, it is a challenge to imitate them realistically. There are numerous approaches available, with different disadvantages and advantages.
Otilia Antal +2 more
doaj +1 more source