Results 61 to 70 of about 911,928 (364)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Shear-induced damped oscillations in an epithelium depend on actomyosin contraction and E-cadherin cell adhesion. [PDF]

open access: yes, 2018
Shear forces between cells occur during global changes in multicellular organization during morphogenesis and tissue growth, yet how cells sense shear forces and propagate a response across a tissue is unknown.
Garcia, Miguel A   +3 more
core   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Perbandingan Pengaruh Pendedahan Uap Bensin Jenis Pertamax Dan Premium Terhadap Gambaran Histologi Bronkus Tikus Putih (Rattus Norvegicus) Jantan

open access: yesMagna Medika, 2019
Bensin yang tersedia di Indonesia adalah bensin jenis Premium dan Pertamax. Bensin Premium mengandung tetra-etil-lead yang terkandung timbal dengan nilai oktan 88 sedangkan Pertamax mengandung metil-tertil-butil-eter atau etil-tertil-butil-eter sebagai ...
Sitilia Muhartiningsih   +1 more
doaj   +1 more source

Expression and function of transient receptor potential channels in the female bovine reproductive tract [PDF]

open access: yes, 2016
© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions.
Atkin, Stephen L.   +3 more
core   +2 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Bronchial Epithelial Cells from Cystic Fibrosis Patients Express a Specific Long Non-coding RNA Signature upon Pseudomonas aeruginosa Infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Pseudomonas aeruginosa (Pa) is the leading cause of chronic lung infection in Cystic Fibrosis (CF) patients. It is well recognized that CF epithelial cells fail to develop an appropriate response to infection, allowing bacterial colonization and a ...
Viviane Balloy   +8 more
doaj   +1 more source

Proteome changes of sheep rumen epithelium during postnatal development

open access: yesFrontiers in Genetics, 2022
Background: The development of the rumen epithelium is a critical physiological challenge for sheep. However, the molecular mechanism underlying postnatal rumen development in sheep remains rarely understood.Results: Here, we used a shotgun approach and ...
Kaizhi Zheng   +8 more
doaj   +1 more source

Code-free development and deployment of deep segmentation models for digital pathology [PDF]

open access: yesarXiv, 2021
Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase commercial solutions. We present a code-free pipeline utilizing free-to-use, open-source software (QuPath, DeepMIB, and FastPathology)
arxiv  

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