FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Dual oxidase 1 is dispensable during Mycobacterium tuberculosis infection in mice
Frontiers in Immunology, 2023 IntroductionMycobacterium tuberculosis (Mtb) is the primary cause of human tuberculosis (TB) and is currently the second most common cause of death due to a singleinfectious agent.
Tuhina Gupta +6 more
doaj +1 more source
The epithelium of the dorsal marginal zone of Xenopus has organizer properties [PDF]
, 1992 We have investigated the properties of the epithelial layer of the dorsal marginal zone (DMZ) of the Xenopus laevis early gastrula and found that it has inductive properties similar to those of the entire Spemann organizer.
Keller, Ray, Shih, John
core
Effect of acute copper sulfate exposure on olfactory responses to amino acids and pheromones in goldfish (Carassius auratus) [PDF]
, 2009 Exposure of olfactory epithelium to environmentally relevant concentrations of copper disrupts olfaction in fish. To examine the dynamics of recovery at both functional and morphological levels after acute copper exposure, unilateral exposure of ...
Baldwin D. H. +52 more
core +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Animal, 2017 The importance of the use of exogenous butyrate in calves’ diets is due to its role as a factor stimulating the functional development of ruminal epithelium and improving calf performance during the transition from preruminant to ruminant status.
B. Niwińska +3 more
doaj +1 more source
Fat2 polarizes the WAVE complex in trans to align cell protrusions for collective migration
eLife, 2022 For a group of cells to migrate together, each cell must couple the polarity of its migratory machinery with that of the other cells in the cohort.
Audrey Miller Williams +3 more
doaj +1 more source
The expression and localization of V-ATPase and cytokeratin 5 during postnatal development of the pig epididymis [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 Objective We examined the localization and expression of H+ pumping vacuolar ATPase (V-ATPase) and cytokeratin 5 (KRT5) in the epididymis of pigs, expressed in clear and basal cells, respectively, during postnatal development.
Yun-Jae Park +9 more
doaj +1 more source
PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. [PDF]
, 2019 Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in ...
Arredondo, Juan +13 more
core
Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. [PDF]
, 2019 Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic drainage and/or bloodstream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood.
Ferreira, Fernando +14 more
core +2 more sources