Results 111 to 114 of about 249 (114)
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The in vitro toxicity of nitrile and epithionitrile derivatives of glucosinolates from swedes (Brassica napus) in human and bovine liver cells

New Zealand Veterinary Journal, 2021
To investigate the direct in vitro toxicity in human and bovine liver cells, and inhibition of activity of ATP-binding cassette transporter G2 (ABCG2) and cytochrome P450 3A4 (CYP3A4) by five nitrile and epithionitrile derivatives from swede (Brassica napus).The following compounds were investigated: 1-cyano-2-hydroxy-3-butene (CHB, epithionitrile ...
I Latimer, R Chand, B Cridge
openaire   +3 more sources

Brassica vegetables as sources of epithionitriles: Novel secondary products formed during cooking

Food Chemistry, 2018
The epithionitriles, 1-cyano-2,3-epithiopropane, in particular, and 1-cyano-3,4-epithiobutane, are important, but yet underestimated glucosinolate hydrolysis products that are released instead of the cancer preventative isothiocyanates in Brassica vegetables, such as cabbage, broccoli, or pak choi.
Franziska S. Hanschen   +6 more
openaire   +3 more sources

The Brassica epithionitrile 1‐cyano‐2,3‐epithiopropane triggers cell death in human liver cancer cells in vitro

Molecular Nutrition & Food Research, 2015
ScopeGlucosinolates are secondary metabolites present in Brassica vegetables. Alkenyl glucosinolates are enzymatically degraded forming nitriles or isothiocyanates, but in the presence of epithiospecifier protein, epithionitriles are released. However, studies on the occurrence of epithionitriles in Brassica food and knowledge about their biological ...
Nina Schlotz   +8 more
openaire   +5 more sources

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