Results 11 to 20 of about 255,440 (257)

Understanding the T cell immune response in SARS coronavirus infection

Emerging Microbes and Infections, 2012
The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%.
Hsueh-Ling Janice Oh, Samuel Ken-En Gan, Antonio Bertoletti, Yee-Joo Tan   +3 more
doaj   +1 more source

Recent Progress Towards a Gonococcal Vaccine

Frontiers in Cellular and Infection Microbiology, 2022
Gonorrhea is a global health concern. Its etiological agent, Neisseria gonorrhoeae, rapidly acquires antimicrobial resistance and does not confer protective immunity as a consequence of infection.
Stavros A. Maurakis, Cynthia Nau Cornelissen   +1 more
doaj   +1 more source

Computational Design of a Novel VLP-Based Vaccine for Hepatitis B Virus

Frontiers in Immunology, 2020
Hepatitis B virus (HBV) is a global virus responsible for a universal disease burden for millions of people. Various vaccination strategies have been developed using viral vector, nucleic acid, protein, peptide, and virus-like particles (VLPs) to ...
Saeed Mobini, Milad Chizari, Ladan Mafakher, Elmira Rismani, Elham Rismani   +4 more
doaj   +1 more source

Identifying New Hybrid Insulin Peptides (HIPs) in Type 1 Diabetes

Frontiers in Immunology, 2021
In 2016 Delong et al. discovered a new type of neoepitope formed by the fusion of two unrelated peptide fragments. Remarkably these neoepitopes, called hybrid insulin peptides, or HIPs, are recognized by pathogenic CD4+ T cells in the NOD mouse and human
Stuart I. Mannering, Stuart I. Mannering, Alan F. Rubin, Alan F. Rubin, Ruike Wang, Pushpak Bhattacharjee   +5 more
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Japanese Encephalitis Virus Vaccination Elicits Cross-Reactive HLA-Class I-Restricted CD8 T Cell Response Against Zika Virus Infection

Frontiers in Immunology, 2020
Japanese encephalitis virus (JEV) exposure or vaccination could elicit cross-reactive CD8 T cell immunity against heterologous flaviviruses in humans.
Marion Tarbe, Marion Tarbe, Wei Dong, Guang Hu, Guang Hu, Yongfen Xu, Yongfen Xu, Jing Sun, Solene Grayo, Solene Grayo, Xianyang Chen, Chengfeng Qin, Jincun Zhao, Li Liu, Li Liu, Xiuzhen Li, Xiuzhen Li, Qibin Leng, Qibin Leng, Qibin Leng   +19 more
doaj   +1 more source

Analisis Epitope Sel T pada SARS-Cov2 dengan Pendekatan Bioinformatika

Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2020
Pada awal tahun 2020 dunia digemparkan dengan tersebarnya wabah secara global yang menyerang pernapasan seperti wabah SARS pada tahun 2003, yaitu COVID-19. Virus penyebab wabah yang bernama SARS-Cov2 ini ternyata memiliki kemiripan ~87.5% dengan SARS-Cov.
Miftahurrahma Rosyda, Faisal Fajri Rahani   +1 more
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Functional epitopes and neutralizing antibodies of vaccinia virus

Frontiers in Microbiology, 2023
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng, Naijing Hu, Yingjun Liu, Cong Xing, Longlong Luo, Xinying Li, Jing Wang, Guojiang Chen, He Xiao, Chenghua Liu, Beifen Shen, Jiannan Feng, Chunxia Qiao   +12 more
doaj   +1 more source

The amino acids differences in epitopes may promote the different allergenicity of ovomucoid derived from hen eggs and quail eggs

Food Science and Human Wellness, 2023
Quail egg ovomucoid can inhibit activation of basophils and eosinophils, while hen egg ovomucoid has been shown to be a major allergen, named Gal d 1. At present, the differences in structure and function between two ovomucoid are unclear.
Mengzhen Hao, Shuai Yang, Shiwen Han, Huilian Che   +3 more
doaj   +1 more source

Identification and profiling of HLA-A*02:01-restricted Toxoplasma gondii peptides through immunopeptidomics in HLA-A2.1 transgenic mice

Virulence
HLA class I presentation of pathogen-derived peptides is essential for CD8+ T-cell recognition of Toxoplasma gondii. While in vitro MHC ligands have been documented, the in vivo ligandome during infection progression remains poorly characterized.
Ruiying Liang, Xinru Luo, Weixiang Xia, Haotian Gu, Dan Li, Yongyu Gao, Zonghui Zuo, Fengshan Gao, Jiabo Ding, Xinming Tang, Zibin Li   +10 more
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Advances in the Characterization of the T-Cell Response to Human Herpesvirus-6

Frontiers in Immunology, 2018
Human herpesvirus (HHV) 6 is thought to remain clinically latent in most individuals after primary infection and to reactivate to cause disease in persons with severe immunosuppression.
Derek J. Hanson, Derek J. Hanson, Joshua A. Hill, Joshua A. Hill, David M. Koelle, David M. Koelle, David M. Koelle, David M. Koelle, David M. Koelle   +8 more
doaj   +1 more source