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Epitope Mapping

Molecular Biotechnology, 1994
Monoclonal antibodies (MAbs) are specific immunological tools because they bind to a precise determinant (the epitope) on the surface of a protein. The procedure of identifying the binding site of a MAb is often termed "epitope mapping."
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Non-Neutralizing Epitopes Shade Neutralizing Epitopes against Omicron in a Multiple Epitope-Based Vaccine

ACS Infectious Diseases, 2022
The ongoing coronavirus disease 2019 pandemic has raised concerns about the risk of re-infection. Non-neutralizing epitopes are one of the major reasons for antibody-dependent enhancement. Past studies on the ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have revealed an infectivity-enhancing site on the ancestral SARS-CoV-2 ...
Hua-Rui Gong   +5 more
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Epitope Mapping

1998
Epitope mapping can be used to identify areas of a protein that an antibody recognizes and binds to. Monoclonal antibodies are easier to characterize, but epitope maps can also be produced for polyclonal antisera.
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An Overview of Epitopes and Methods for Antibody Epitope Mapping

Antibodies are protein molecules indispensable for many therapeutic, diagnostic, and research purposes due to their exquisite ability to selectively recognize and bind a given antigen. The particular area of the antigen recognized by the antibody is called the epitope, and mapping of such epitopes can provide important mechanistic insights and indicate
Johan, Nilvebrant   +3 more
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A question of epitope

Journal of Neuroimmunology, 1985
N, Murray   +3 more
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Epitope Peptides and Immunotherapy

Current Protein & Peptide Science, 2007
Allergic diseases affect atopic individuals, who synthesize specific Immunoglobulins E (IgE) to environmental allergens, usually proteins or glycoproteins. These allergens include grass and tree pollens, indoor allergens such as house dust mites and animal dander, and various foods.
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epitope3D: a machine learning method for conformational B-cell epitope prediction

Briefings in Bioinformatics, 2022
Douglas Pires   +2 more
exaly  

Advances in epitope mapping technologies for food protein allergens: A review

Trends in Food Science and Technology, 2021
Shudong He, Hanju Sun
exaly  

Linear B-Cell Epitope Prediction for In Silico Vaccine Design: A Performance Review of Methods Available via Command-Line Interface

International Journal of Molecular Sciences, 2021
Nikos Papandreou   +2 more
exaly  

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