Development of a novel multi-epitope peptide vaccine candidate against <i>Mycobacterium tuberculosis</i> using reverse vaccinology. [PDF]
Hasan NA +2 more
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Identification of tumor-associated antigens with multi-cancer therapeutic potential. [PDF]
Wickland DP +10 more
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The impact of biologically relevant negative samples on machine learning-based B-cell epitope prediction for Influenza A. [PDF]
Pareja-Barrueto C +5 more
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Comparing CD8+ T cell ENV epitopes of two HLA class I alleles associated with different outcomes of HIV-1 infection with broadly neutralizing antibodies epitope targets discovered to date. [PDF]
Ramdoyal A +4 more
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SPAID: a comprehensive database for disease-specific autoantigens in autoimmune disorders. [PDF]
Deng S +9 more
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Preliminary Immunogenicity Evaluation of an Immunoinformatics-Guided Multi-Epitope mRNA Vaccine Against Porcine Epidemic Diarrhea Virus. [PDF]
Liu Y, Huang H, Chen Y, Shu J, Wu F.
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Design and preparation of multi-epitope mRMA vaccine for Brucella VirB8, OMO25 and other proteins
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An epitope is defined as the site on an antigen at which an antibody binds. In the case of proteins the epitopes can be classified as continuous (or sequential) and discontinuous according to whether or not the amino acids recognized are close together in the primary sequence or are well-separated but brought together by the folding of the protein. The
J E, Heckels, M, Christodoulides
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The immune response to extrinsic and intrinsic antigens involves specific antigen receptors on T and B cells. The precise antigenic determinants, or epitopes, recognized by these receptors are discrete sequences within the native antigen. The ability to identify and manufacture key epitopes in the immune response has important implications for disease ...
A C, Horsfall +3 more
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