Results 51 to 60 of about 258,671 (306)

Immunoproteomics Reveals Pathogen’s Antigens Involved in Homo sapiens–Histoplasma capsulatum Interaction and Specific Linear B-Cell Epitopes in Histoplasmosis

Frontiers in Cellular and Infection Microbiology, 2020
Histoplasmosis is one of the most frequent systemic mycosis in HIV patients. In these patients, histoplasmosis has high rates of morbidity/mortality if diagnosis and treatment are delayed.
Marcos Abreu Almeida, Rodrigo Almeida-Paes, Allan Jefferson Guimarães, Richard Hemmi Valente, Célia Maria de Almeida Soares, Rosely Maria Zancopé-Oliveira   +5 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Revolutionizing the virulent protein Internalin a in Listeria monocytogenes and designing multi epitope-based vaccine via immunoinformatic approaches

CyTA - Journal of Food
This study addresses the crucial protein Internalin A in the development of a possible vaccination against Listeria monocytogenes. A meticulous in silico strategy was used which included physiochemical analysis, epitope prediction, and molecular ...
Tariq Aziz, Muhammad Naveed, Muhammad Aqib Shabbir, Khizra Jabeen, Athina S. Tzora, Eleftherios Bonos, Ioannis Skoufos, Metab Alharbi, Abdullah F Alasmari, Abdulrahman Alshammari   +9 more
doaj   +1 more source

A Basic Molecular Analysis of the Diabetic Antigen GAD by Homology Modelling. Principles of the Method and Understanding of Antigenicity and Binding Sites

Pteridines, 2007
Functional specificity of a protein is linked to its structure. A growing section of bioinformatics deals with the prediction and visualization of protein 3D structures.
Wiltgen Marco, Tilz Gernot P.
doaj   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

CoronaVR: A Computational Resource and Analysis of Epitopes and Therapeutics for Severe Acute Respiratory Syndrome Coronavirus-2

Frontiers in Microbiology, 2020
In December 2019, the Chinese city of Wuhan was the center of origin of a pneumonia-like disease outbreak with an unknown causative pathogen. The CDC, China, managed to track the source of infection to a novel coronavirus (2019-nCoV; SARS-CoV-2) that ...
Amit Kumar Gupta, Md. Shoaib Khan, Shubham Choudhury, Adhip Mukhopadhyay, Adhip Mukhopadhyay, Sakshi, Sakshi, Amber Rastogi, Amber Rastogi, Anamika Thakur, Anamika Thakur, Pallawi Kumari, Manmeet Kaur, Shalu, Chanchal Saini, Vandna Sapehia, Barkha, Pradeep Kumar Patel, Kailash T. Bhamare, Manoj Kumar, Manoj Kumar   +20 more
doaj   +1 more source

ACRMGroup/epitopes v1.0

, 2018
<p>Code and data for our paper on analysis of epitope discontinuity and conformation:</p> <p><strong>B-cell Epitopes: Discontinuity and Conformational Analysis</strong></p> <p>Saba Ferdous<sup>a,b</sup&
Saba Ferdous (8224479), Andrew Martin, Saba Ferdous, Andrew Martin (43126)   +3 more
core   +1 more source

De Novo generation of escape Variant-specific CD8+ T-Cell responses following Cytotoxic T-Lymphocyte escape in chronic Human Immunodeficiency Virus Type 1 Infection [PDF]

, 2005
Human immunodeficiency virus type 1 (HIV-1) evades CD8+ T-cell responses through mutations within targeted epitopes, but little is known regarding its ability to generate de novo CD8+ T-cell responses to such mutants.
Allgaier, R.L., Cheng, M., Galit Alter, Altfeld, M., Elizabeth T. Kalife, Frahm, N., Xu G. Yu, Kalife, E.T., Marcus Altfeld, Michael Cheng, Yu, X.G., Walker, B.D., Laura L. Reyor, Mui, S., Allen, T.M., Reyor, L.L., Christian Brander, Alter, G., Mathias Lichterfeld, Eric S. Rosenberg, Rachel L. Allgaier, Todd M. Allen, Simon A. Mallal, Nancy V. Brown, John, M., Nicole Frahm, Johnston, M.N., Rosenberg, E.S., Brown, N.V., Brander, C., Bruce D. Walker, Mina John, Mary N. Johnston, Mallal, S.A., Stanley Mui, Lichterfeld, M.   +35 more
core   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Computational Prediction of B-cell Epitopes of Mycobacterium tuberculosis-Implications in Vaccine Design

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis. Bacillus Calmette-Guérin is the only vaccine available for TB.
Esakkimuthu THANGAMARIAPPAN, Manikandan MOHAN, Krishnan SUNDAR   +2 more
doaj   +1 more source