Results 31 to 40 of about 4,322 (264)

Epothilones Suppress Neointimal Thickening in the Rat Carotid Balloon-Injury Model by Inducing Vascular Smooth Muscle Cell Apoptosis through p53-Dependent Signaling Pathway.

PLoS ONE, 2016
Microtubule stabilizing agents (MTSA) are known to inhibit vascular smooth muscle cell (VSMC) proliferation and migration, and effectively reduce neointimal hyperplasia and restenosis.
Dong Ju Son, Jae Chul Jung, Jin Tae Hong
doaj   +1 more source

Shared and Unique Determinants of the Erythropoietin (EPO) Receptor Are Important for Binding EPO and EPO Mimetic Peptide [PDF]

Journal of Biological Chemistry, 1999
We have shown previously that Phe93 in the extracellular domain of the erythropoietin (EPO) receptor (EPOR) is crucial for binding EPO. Substitution of Phe93 with alanine resulted in a dramatic decrease in EPO binding to the Escherichia coli-expressed extracellular domain of the EPOR (EPO-binding protein or EBP) and no detectable binding to full-length
S A, Middleton, F P, Barbone, D L, Johnson, R L, Thurmond, Y, You, F J, McMahon, R, Jin, O, Livnah, J, Tullai, F X, Farrell, M A, Goldsmith, I A, Wilson, L K, Jolliffe   +12 more
openaire   +2 more sources

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

Arthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk, Jing Li, Cathy Nasrallah, Cherish Wilson, Alicia Hamblin, Christine Hariz, Cammie Young, Stephen Shiboski, Emma Kersey, Mary Nakamura, Judith F. Ashouri, Mehrdad Matloubian, Andrew J. Gross, Jennifer Barton, Beth Berrean, Jonathan Prugh, Jinoos Yazdany   +16 more
wiley   +1 more source

Istiqlol Davri O'zbek She'riyatida Folklor Sintezi

Comparative Turkish Dialects and Literatures
Maqolada istiqlol davri o’zbek she’riyatida folklor sinteziga murojaat qilish tamoyilining kuchayishi, mazkur davrda ijod qilgan shoirlar folklorga xos an’analar, janrlar, obrazlar, mifologik qarashlar sintezi orqali davr muammolarini yoritishga erisha ...
Zilola Eshanova
doaj   +1 more source

Probleme des Studiums des Kalmückischen heldenhaften epos «Dzhangar» am Anfang des 21. Jahrhunderts

Nomadic Civilization: Historical Research, 2021
The Kalmyk people are the creators and protectors of the richest oral and poetic creativity. It is presented with diverse folk genres: with fairy tales, songs, proverbs, riddles, congratulations, magtal praises. The most valuable pearl of Kalmyk folklore
T. G. Basangova
doaj   +1 more source

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

Arthritis Care &Research, EarlyView.
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel, Tripti Singh, Meredith Ingersoll, Shelby Gomez, Amanda Weber, Sarah E. Panzer, Sancia Ferguson, Christie M. Bartels, Shivani Garg   +8 more
wiley   +1 more source

Destan û Hikayeyên Gelêrî: Niqaş û Nirxandinek li ser Cureyên Edebiyata Kurdî ya Gelêrî

Nubihar Akademi
Mijara vê gotarê di çarçoveya niqaşên derbarê cureyê de nirxandina gengeşiya binavkirina “hikayeyên gelêrî” û “destan”ê ye di edebiyata kurdî ya gelêrî de. Mijara cureyan û binavkirina wan di nav xebatên folklorê de mijareke giring e.
Necat Keskin
doaj   +1 more source

Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis [PDF]

Expert Opinion on Therapeutic Targets, 2015
Recombinant human erythropoietin (rhEPO) is a first-line therapeutic for the anemia of chronic kidney disease, cancer chemotherapy, AIDS (Zidovudine therapy), and lower-risk myelodysplastic syndrome. However, rhEPO frequently elevates hypertension, is costly, and may affect cancer progression.
Nicole, Rainville, Edward, Jachimowicz, Don M, Wojchowski   +2 more
openaire   +2 more sources

Unraveling MXene Oxidation Mechanisms Under Realistic Gas Environments by In Situ Gas‐Cell TEM

Advanced Functional Materials, EarlyView.
Real‐time visualization of MXene degradation reveals a fundamental oxidation mechanism under oxygen and moisture environments. Using in situ gas‐cell electron microscopy, this study demonstrates that oxygen degradation drives a thermodynamically controlled high‐temperature transformation into mixed rutile/anatase phases.
Yongfa Cheng, Kunmo Koo, Zizhen Cai, Paty Meza, Yu Wen, Byungseok Seo, Yukun Liu, Xiaobing Hu, Vinayak P. Dravid   +8 more
wiley   +1 more source

Programmable Stepwise Heteroepitaxial Growth of Colloidal Crystals With Different Phases

Advanced Materials, EarlyView.
Stepwise heteroepitaxial growth is adapted to colloidal crystal engineering with DNA, enabling face‐centered cubic (fcc) facets to grow on body‐centered cubic (bcc) crystals with 110 facets. This approach tolerates large lattice mismatches, extending heteroepitaxy beyond the limits of conventional atomic systems.
Xiaowei Liu, Yuanwei Li, Ramin Yazdaanpanah, Ye Zhang, Rachel R. Chan, Xiaobing Hu, Yiming Yang, Vinayak P. Dravid, Koray Aydin, Chad A. Mirkin   +9 more
wiley   +1 more source