Results 171 to 180 of about 260,645 (332)

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Plant-pathogen interactions during infection process of asparagus with Fusarium spp.

Open Life Sciences, 2013
Waśkiewicz Agnieszka, Irzykowska Lidia, Drzewiecka Kinga, Bocianowski Jan, Dobosz Bernadeta, Weber Zbigniew, Karolewski Zbigniew, Krzyminiewski Ryszard, Goliński Piotr   +8 more
doaj   +1 more source

Clinical EPR [PDF]

Academic Radiology, 2014
Harold M. Swartz, Benjamin B. Williams, Bassem I. Zaki, Alan C. Hartford, Lesley A. Jarvis, Eunice Y. Chen, Richard J. Comi, Marc S. Ernstoff, Huagang Hou, Nadeem Khan, Steven G. Swarts, Ann B. Flood, Periannan Kuppusamy   +12 more
openaire   +1 more source

Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine

Advanced Science, EarlyView.
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu, Xiaoyue Xu, Dan Xu, Hui Zhang, Nan Wang, Yang Yang, Qian Chen, Shunjie Chen, Cheng Li   +8 more
wiley   +1 more source

Probing Oxygen Reduction Mechanism of Copper/Triazoles Complexes Based Electrocatalysts By EPR Spectroscopy [PDF]

, 2013
Congling Zhang, Jamie S. Lawton, Thomas A. Zawodzinski   +2 more
openalex   +1 more source

Synergistic Modulation of Ru–O Bond Covalency via Ba/Fe Co‐Doping and Oxygen‐Vacancy Engineering for Efficient Wide‐pH Oxygen Evolution

Advanced Science, EarlyView.
Ba/Fe co‐doping and oxygen vacancy engineering synergistically modulate the Ru–O bond covalency in RuO2, leading to markedly enhanced OER activity across wide‐pH electrolytes. ABSTRACT Developing efficient and stable oxygen evolution reaction (OER) catalysts across a wide‐pH range is critical for practical water electrolysis.
Zongpeng Wang, Ting Jiang, Reem F. Alshehri, Longfei Ding, Salah M. El‐Bahy, Yuanmo Lin, Puyou Ying, Hongxiang Chen, Hanhui Lei, Terence X. Liu, Zhiping Lin   +10 more
wiley   +1 more source

Photoinduced proton transfer in differently structured water: an EPR approach to solving a classic problem. [PDF]

Sci Rep
Barbon A, Savitsky A, Grigoriev IA, Reznikov VA, Kirilyuk IA, Lushchekina S, Moroz IB, Eliash T, Friedman N, Sheves M, Carmieli R, Weiner L.   +11 more
europepmc   +1 more source

Badanie metodą EPR funkcjonalizowanych nanocząstek magnetytu w surowicy i pełnej krwi ludzkiej

, 2016
Tomasz Kubiak
openalex   +1 more source

Epr Of Gamma-irradiated Single-crystals Of Calcium-tungstate Doped With Tantalum Ions.

, 1974
Samuel Rafael Irizarry-milan
openalex   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source