First Combined in Vivo X-Ray Tomography and High-Resolution Molecular Electron Paramagnetic Resonance (EPR) Imaging of the Mouse Knee Joint Taking into Account the Disappearance Kinetics of the EPR Probe [PDF]
Molecular Imaging, 2012 Although laboratory data clearly suggest a role for oxidants (dioxygen and free radicals derived from dioxygen) in the pathogenesis of many age-related and degenerative diseases (such as arthrosis and arthritis), methods to image such species in vivo are
Nicolas Bézière +14 more
doaj +4 more sources
Concurrent Longitudinal EPR Monitoring of Tissue Oxygenation, Acidosis, and Reducing Capacity in Mouse Xenograft Tumor Models [PDF]
Cell Biochemistry and Biophysics, 2017 Tissue oxygenation, extracellular acidity and tissue reducing capacity are among crucial parameters of tumor microenvironment (TME) of significant importance for tumor pathophysiology.
Denko, Nicholas C. +3 more
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EPR quantification of vascular nitric oxide production in genetically modified mouse models.
Nitric Oxide, 2016 With increasing use of genetically modified mice to study endothelial nitric oxide (NO) biology, methods for reliable quantification of vascular NO production by mouse tissues are crucial. We describe a technique based on electron paramagnetic resonance (
Khoo, J +7 more
core +4 more sources
Non-invasive Measurement of Melanin-Derived Radicals in Living Mouse Tail Using X-band EPR [PDF]
Non-invasive Measurement of Melanin-Derived Radicals in Living Mouse Tail Using X-band EPRThe aim of this experiment is to measure in vivo generation of melanin-derived radicals non-invasively, as a quantifiable index of radio-biological effect.
関根 絵美子 +21 more
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EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model [PDF]
Cell Biochemistry and Biophysics, 2017 Abstract Head and neck squamous cell carcinoma (HNSCC) tumours are associated with high mortality despite advances in therapy. The monoclonal antibody cetuximab (Erbitux®) has been approved for the treatment of advanced HNSCC. However, only a subset of HNSC patients receiving cetuximab actually responds to treatment, underlining the need ...
H. Gustafsson +5 more
openaire +5 more sources
Antioxidant Activity of Chlorogenic Acid Evaluated via EPR Spectroscopy and Its Visual Tracking in Mouse Kidney. [PDF]
NutrientsBackground/Objectives: Chlorogenic acid (CGA) is a natural antioxidant widely distributed in various plant foods, exhibiting great potential for the development of natural antioxidant agents and biomedical applications. Methods: In this study, the antioxidant activity of CGA was first characterized via electron paramagnetic resonance (EPR) spectroscopy
Quan L +5 more
europepmc +3 more sources
HF-EPR, Raman, UV/VIS light spectroscopic, and DFT studies of the ribonucleotide reductase R2 tyrosyl radical from Epstein-Barr virus. [PDF]
PLoS ONE, 2011 Epstein-Barr virus (EBV) belongs to the gamma subfamily of herpes viruses, among the most common pathogenic viruses in humans worldwide. The viral ribonucleotide reductase small subunit (RNR R2) is involved in the biosynthesis of nucleotides, the DNA ...
Ane B Tomter +7 more
doaj +1 more source
Partial acquisition of 4D spectral-spatial EPR imaging
, 2023 These files are the data regarding the work, entitled "Partial acquisition of spectral projections accelerates four-dimensional spectral-spatial EPR imaging for mouse tumor models: A feasibility study.
Hiroshi Hirata
core +2 more sources
Mapping of redox status in a brain‐disease mouse model by three‐dimensional EPR imaging [PDF]
Magnetic Resonance in Medicine, 2010 AbstractElectron paramagnetic resonance imaging using nitroxides is a powerful method for visualizing the redox status modulated by oxidative stress in vivo. Typically, however, data acquisition times have been too slow to obtain a sufficient number of projections for three‐dimensional images, when using continuous wave‐electron paramagnetic resonance ...
Hirotada, Fujii +3 more
openaire +2 more sources
Copper-organic binder complexes in pigments: an EPR study [PDF]
, 2022 openCopper-based pigments have been used for a long time as blue or green colors by many artists. They are involved in darkening and general deterioration processes both of pigments themselves and of supporting material.
PUNIS, RICCARDO
core