Results 31 to 40 of about 947,323 (274)

EPR Everywhere

, 2021
This review is inspired by the contributions from the University of Denver group to low field EPR, in honor of Professor Gareth Eaton s 80th birthday. The goal is to capture the spirit of innovation behind the body of work, especially as it pertains to ...
Biller, J.R., McPeak, J.E., Joseph E. McPeak, Joshua R. Biller   +3 more
core   +1 more source

Reactive oxygen species-activated nanoprodrug of Ibuprofen for targeting traumatic brain injury in mice. [PDF]

PLoS ONE, 2013
Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI recorded annually by the Centers for Disease Control. However, TBI has proven to be an extremely challenging condition to treat.
Morgan A Clond, Bong-Seop Lee, Jeffrey J Yu, Matthew B Singer, Takayuki Amano, Alexander W Lamb, Doniel Drazin, Babak Kateb, Eric J Ley, John S Yu   +9 more
doaj   +1 more source

Preclinical modeling of low energy X-rays radiological burn: Dosimetry study by monte carlo simulations and EPR spectroscopy

Frontiers in Physiology, 2022
Interventional radiology has grown considerably over the last decades and become an essential tool for treatment or diagnosis. This technique is mostly beneficial and mastered but accidental overexposure can occur and lead to the appearance of ...
Manon Guillou, Bruno L’Homme, François Trompier, Gaëtan Gruel, Yolanda Prezado, Morgane Dos Santos   +5 more
doaj   +1 more source

Application of Electron Paramagnetic Resonance (EPR) Oximetry to Monitor Oxygen in Wounds in Diabetic Models.

PLoS ONE, 2015
A lack of oxygen is classically described as a major cause of impaired wound healing in diabetic patients. Even if the role of oxygen in the wound healing process is well recognized, measurement of oxygen levels in a wound remains challenging.
Céline M Desmet, Aurore Lafosse, Sophie Vériter, Paolo E Porporato, Pierre Sonveaux, Denis Dufrane, Philippe Levêque, Bernard Gallez   +7 more
doaj   +1 more source

Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1. [PDF]

PLoS ONE, 2009
Mouse aldehyde oxidase (mAOX1) forms a homodimer and belongs to the xanthine oxidase family of molybdoenzymes which are characterized by an essential equatorial sulfur ligand coordinated to the molybdenum atom. In general, mammalian AOs are characterized
Silvia Schumann, Mineko Terao, Enrico Garattini, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Silke Leimkühler   +6 more
doaj   +1 more source

Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate. [PDF]

PLoS ONE, 2012
The enzyme ribonucleotide reductase (RNR) catalyzes the conversion of ribonucleotides to deoxyribonucleotides, the precursors for DNA. RNR requires a thiyl radical to activate the substrate.
Guro K Sandvik, Ane B Tomter, Jonas Bergan, Giorgio Zoppellaro, Anne-Laure Barra, Asmund K Røhr, Matthias Kolberg, Stian Ellefsen, K Kristoffer Andersson, Göran E Nilsson   +9 more
doaj   +1 more source

A versatile technique for the in vivo imaging of human tumor xenografts using near-infrared fluorochrome-conjugated macromolecule probes. [PDF]

PLoS ONE, 2013
Here, we present a versatile method for detecting human tumor xenografts in vivo, based on the enhanced permeability and retention (EPR) effect, using near-infrared (NIR) fluorochrome-conjugated macromolecule probes.
Hiroshi Suemizu, Kenji Kawai, Yuichiro Higuchi, Haruo Hashimoto, Tomoyuki Ogura, Toshio Itoh, Erika Sasaki, Masato Nakamura   +7 more
doaj   +1 more source

Spectroscopic studies of the iron and manganese reconstituted tyrosyl radical in Bacillus cereus ribonucleotide reductase R2 protein.

PLoS ONE, 2012
Ribonucleotide reductase (RNR) catalyzes the rate limiting step in DNA synthesis where ribonucleotides are reduced to the corresponding deoxyribonucleotides.
Ane B Tomter, Giorgio Zoppellaro, Caleb B Bell, Anne-Laure Barra, Niels H Andersen, Edward I Solomon, K Kristoffer Andersson   +6 more
doaj   +1 more source

Crystal structure of a DNA containing the planar, phenoxazine-derived bi-functional spectroscopic probe Ç [PDF]

, 2011
Electron Paramagnetic Resonance (EPR) spectroscopy and fluorescence spectroscopy are complementary biophysical techniques used to examine the structure and dynamics of macromolecules.
Reginsson, Gunnar Widtfeldt, Olav Schiemann, Cekan, Pavol, Shelke, Sandip A., Adrian R. Ferré-D’Amaré, Gunnar W. Reginsson, Pavol Cekan, Edwards, Thomas E., Snorri Th. Sigurdsson, Schiemann, Olav, Sigurdsson, Snorri, Thomas E. Edwards, Ferre D'Amare, Adrian R., Sandip A. Shelke   +13 more
core   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source