Results 241 to 250 of about 947,323 (274)

EPR Detection of Free Radicals in UV‐lrradiated Skin: Mouse Versus Human

Photochemistry and Photobiology, 1996
Abstract— Ultraviolet radiation produces free radicals in Skh‐1 mouse skin, contributing to photoaging and carcinogenesis. If a mouse model is a general indicator of free radical processes in human skin photobiology, then radical production observed in mouse and human skin should be directly comparative.
B A, Jurkiewicz, G R, Buettner
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Analyzing heme proteins using EPR techniques: the heme-pocket structure of ferric mouse neuroglobin

JBIC Journal of Biological Inorganic Chemistry, 2006
In this work, an electron paramagnetic resonance (EPR) strategy to study the heme-pocket structure of low-spin ferric heme proteins is optimized. Frozen solutions of ferric mouse neuroglobin (mNgb) are analyzed by means of electron spin echo envelope modulation and pulsed electron-nuclear double resonance techniques.
Vinck, E., Van Doorslaer, S., Dewilde, S., Mitrikas, G., Schweiger, A., Moens, L.   +5 more
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Variation in Blood Oxygenation and Cerebral pO2 in a Mouse Model Measured by EPR Spectrometry

2003
The partial pressure of oxygen (p02) is one of the most important parameters in many physiological and pathological processes. As a highly aerobic organ, the brain is very sensitive to changes in oxygen availability. The importance of a sufficient oxygen supply is reflected in the brain through many complex mechanisms that ensure adequate blood flow ...
Matthew P, Thomas, Simon K, Jackson, Philip E, James   +2 more
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An EPR method for estimating activity of antioxidants in mouse skin using an anthralin-derived radical model

Free Radical Research, 2009
Inhibitory effects of intravenously or orally administered antioxidants on the anthralin-derived radical generated in skin (mainly in the epidermis) of living mice by ultraviolet-A (UVA) irradiation were estimated. Anthralin was applied to the dorsal skin of living mice and the mice were then exposed to UVA.
Sayo, Kawai, Ken-Ichiro, Matsumoto, Hideo, Utsumi   +2 more
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In Vivo/Ex Vivo EPR Investigation of the Brain Redox Status and Blood-Brain Barrier Integrity in the 5xFAD Mouse Model of Alzheimer's Disease

Current Alzheimer Research, 2021
Background: Alzheimer’s disease (AD) is the most common neurodegenerative disorder characterized by cognitive decline and total brain atrophy. Despite the substantial scientific effort, the pathological mechanisms underlying neurodegeneration in AD are currently unknown.
Vesković, Ana, Nakarada, Đura, Pavićević, Aleksandra, Prokić, Bogomir, Perović, Milka, Kanazir, Selma, Popović-Bijelić, Ana, Mojović, Miloš   +7 more
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Imaging spin probe distribution in the tumor of a living mouse with 250 MHz EPR: Correlation with BOLD MRI

Magnetic Resonance in Medicine, 2002
AbstractElectron paramagnetic resonance imaging (EPRI) promises to provide new insights into the physiology of tissues in health and disease. Understanding the in vivo imaging capability of this new modality requires comparison with other physiologically responsive techniques.
Benjamin B, Williams, Hania, al Hallaq, G V R, Chandramouli, Eugene D, Barth, Jonathan N, Rivers, Marta, Lewis, Valeri E, Galtsev, Gregory S, Karczmar, Howard J, Halpern   +8 more
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EPR Study of Mouse Tissues in Search for Adaptive Responses to Low Level Whole-body X-irradiation

International Journal of Radiation Biology, 1992
Effect of a low dose of whole-body X-irradiation (D1 = 0.075 Gy) of mice on some biochemical changes induced in the spleen and thymus by a subsequent challenge dose (D2 = 1.5 Gy) was studied by electron paramagnetic resonance (EPR). Kunming and SHK mice were used.
D A, Svistuneko, G Z, Ju, J, Wei, J S, Zhang, S Z, Liu   +4 more
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Dynamic changes in the distribution and time course of blood–brain barrier-permeative nitroxides in the mouse head with EPR imaging: visualization of blood flow in a mouse model of ischemia

Free Radical Biology and Medicine, 2014
Electron paramagnetic resonance (EPR) imaging using nitroxides as redox-sensitive probes is a powerful, noninvasive method that can be used under various physiological conditions to visualize changes in redox status that result from oxidative damage. Two blood-brain barrier-permeative nitroxides, 3-hydroxymethyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl ...
Miho C, Emoto, Hideo, Sato-Akaba, Hiroshi, Hirata, Hirotada G, Fujii   +3 more
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EPR and multi-field magnetisation of reduced forms of the binuclear iron centre in ribonucleotide reductase from mouse

JBIC Journal of Biological Inorganic Chemistry, 1996
Mouse ribonucleotide reductase is composed of a 1 : 1 complex of two homodimeric subunits and catalyses the first unique step on the biochemical pathway to DNA synthesis. The small subunit, protein R2, contains dinuclear iron-oxygen clusters and a tyrosyl free radical required for catalytic activity.
M. Atta, Noële Debaecker, K. K. Andersson, Jean-Marc Latour, Lars Thelander, Astrid Gräslund   +5 more
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A novel ascorbic acid-resistant nitroxide in fat emulsion is an efficient brain imaging probe forin vivoEPR imaging of mouse

Free Radical Research, 2011
The loss of paramagnetism of nitroxide radicals due to reductant reactions in biological systems, places a fundamental time constraint on their application as an imaging probe in in vivo EPR imaging studies. However, in vitro studies of the newly synthesized tetraethyl-substituted piperidine nitroxide radical demonstrated high resistivity to ...
Miho, Emoto, Fumiya, Mito, Toshihide, Yamasaki, Ken-Ichi, Yamada, Hideo, Sato-Akaba, Hiroshi, Hirata, Hirotada, Fujii   +6 more
openaire   +2 more sources