Results 181 to 190 of about 108,615 (251)

Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song   +10 more
wiley   +1 more source

Exogenous Epstein-Barr virus nuclear antigen 1 induces ADAR1-driven tumor resistance against immunotherapy. [PDF]

open access: yesSignal Transduct Target Ther
Liu C   +20 more
europepmc   +1 more source

Clinical Application of Peripheral Blood Biomarkers for Solid Tumors

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Peripheral blood biomarkers provide a minimally invasive, dynamic, and potentially more accurate means to obtain a comprehensive tumor profile. Technologies for detecting them are advancing, and with the help of artificial intelligence, they are being used more and more often for cancer diagnosis, prognostic assessment, and therapeutic monitoring ...
Xinru Tu, Mengyan Tu, Junfen Xu
wiley   +1 more source

Onset of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis triggered by sudden reactivation of asymptomatic latent Epstein-Barr virus infection. [PDF]

open access: yesHematol Transfus Cell Ther
Mizuki M   +14 more
europepmc   +1 more source

Systematic Identification of Molecular Signatures Dictating Therapeutic Effects of Clinically First‐Line Chemotherapy Regimens for Human Gastric Cancer Patients Based on Organoid Model

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Chemotherapy is the mainstay in the treatment of advanced gastric cancer (GC); yet, GC showed diverse responses to first‐line chemotherapy regimens and the underlying molecular basis is still not clear. Here, we established a system that combined organoid‐based chemotherapy regimen screening and transcriptome‐based evaluation to identify underlying ...
Jingwei Yang   +14 more
wiley   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

open access: yesMedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng   +8 more
wiley   +1 more source

Evaluating the need for Epstein-Barr virus DNAemia monitoring in liver transplant recipients in India. [PDF]

open access: yesMicrobiol Spectr
Agarwal R   +6 more
europepmc   +1 more source

The Global Burden of Leukemia, 1990–2021: A Systematic Analysis of Prevalence, DALYs, and Risk Factors From the Global Burden of Disease Study

open access: yesMed Research, Volume 2, Issue 1, Page 75-88, March 2026.
Using data from the Global Burden of Disease Study 2021, we systematically assessed leukemia prevalence and disability‐adjusted life years (DALYs) across 204 countries and territories from 1990 to 2021, stratified by subtype, demographics, and risk factors.
Yuping Wu   +8 more
wiley   +1 more source

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