Results 211 to 220 of about 1,388,067 (303)

Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia

open access: yesOral Diseases, EarlyView.
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio   +8 more
wiley   +1 more source

Biological Biomarkers in Proliferative Verrucous Leukoplakia: A Systematic Review and Meta‐Analysis

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To synthesise biological biomarker evidence in proliferative verrucous leukoplakia/proliferative leukoplakia and quantify malignant transformation using eligible longitudinal evidence. Methods Primary human biomarker studies and longitudinal studies reporting extractable malignant‐transformation events and denominators were ...
Madawi Faisal Alkeheli, Hisham I. Othman
wiley   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan   +8 more
wiley   +1 more source

The lymphocyte function of allogeneic peripheral blood stem cell grafts is associated with relapse and cytomegalovirus reactivation

open access: yesTransfusion, EarlyView.
Abstract Background Allogeneic hematopoietic stem cell transplantation (HSCT) is a treatment primarily for hematological malignancies. Infections, relapse, and graft versus host disease (GvHD) are some of the most common adverse events following HSCT. We aimed to evaluate whether the lymphocyte function of the stem cell graft was associated with these ...
Anna Söderström   +8 more
wiley   +1 more source

Passive acquisition of hepatitis B virus antibodies after allogeneic hematopoietic cell transplantation

open access: yesTransfusion, EarlyView.
Abstract Background Newly positive hepatitis B virus (HBV) serologic results after allogeneic hematopoietic cell transplantation (HCT) may reflect passive antibody transfer from blood‐derived products rather than HBV infection. We investigated the incidence and temporal patterns of hepatitis B surface antibody (anti‐HBs) and antibody to hepatitis B ...
Takaaki Konuma   +7 more
wiley   +1 more source

In the Midst of a Cytokine Storm—The Hemophagocytic Syndrome (Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome)

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Hemophagocytic syndrome (HPS)/hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome characterized by immune dysregulation, cytokine overproduction, hemophagocytosis, cytopenias, and multiorgan dysfunction.
Joanne B. Messick
wiley   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

open access: yesExperimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė   +10 more
wiley   +1 more source

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