Results 41 to 50 of about 108,615 (251)

Chronic Epstein-Barr viral infection in children: a clinical case

open access: yesМедицинский совет, 2021
The urgency of Epstein-Barr virus infection is explained by wide circulation of Epstein-Barr virus among children and adults, its tropism to immunocompetent cells with lifelong persistence after primary infection and polymorphism of clinical ...
S. P. Kokoreva   +2 more
doaj   +1 more source

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu   +6 more
wiley   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel   +13 more
wiley   +1 more source

Immune-checkpoint expression in Epstein-Barr virus positive and negative plasmablastic lymphoma: a clinical and pathological study in 82 patients

open access: yesHaematologica, 2016
Plasmablastic lymphoma is a rare and aggressive diffuse large B-cell lymphoma commonly associated with Epstein-Barr virus co-infection that most often occurs in the context of human immunodeficiency virus infection.
Camille Laurent   +15 more
doaj   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole‐Blood RNA Transcriptome

open access: yesArthritis &Rheumatology, EarlyView.
Objective Antiphospholipid syndrome (APS) is a thromboinflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)–positive patients using whole‐blood transcriptomics.
Amala Ambati   +13 more
wiley   +1 more source

Mature T‐cell leukemia/lymphoma with an NK‐like immunophenotype: A report of 7 cases

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Distinguishing T‐cell from NK‐cell neoplasms can occasionally be challenging, as neoplastic T cells can lose T‐cell markers such as surface CD3 (sCD3) and CD5 while acquiring NK‐cell markers such as CD16, CD56, and CD94. In this study, we present a series of 7 mature T‐cell lymphoma/leukemia cases with NK‐like immunophenotypes to clarify ...
Wei J. Wang   +8 more
wiley   +1 more source

Atypical manifestations of Epstein–Barr virus in children: a diagnostic challenge

open access: yesJornal de Pediatria, 2016
Objective: Clarify the frequency and the pathophysiological mechanisms of the rare manifestations of Epstein–Barr virus infection. Sources: Original research studies published in English between 1985 and 2015 were selected through a computer-assisted ...
Vasileios Bolis   +4 more
doaj   +1 more source

Phagocytic Mesothelial Cells in Pericardial Effusion Following Allogeneic Peripheral Blood Stem Cell Transplantation for Chronic Active Epstein–Barr Virus Infection: A Distinctive Cytomorphological and Immunocytochemical Case Study

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Phagocytic activity of mesothelial cells is a rare phenomenon requiring careful differentiation from histiocytic hemophagocytosis to ensure appropriate patient management, as these phenomena could exhibit distinct clinical implications. In this study, we report a case of phagocytic mesothelial cells found in pericardial effusion that developed
Hidetoshi Satomi   +5 more
wiley   +1 more source

DETECTION OF EPSTEIN BARR VIRUS IN RENAL TRANSPLANT RECIPIENTS: TWO CENTERS STUDY

open access: yesThe Iraqi Journal of Medical Sciences
Background:Viruses are among the most common causes of opportunistic infections after transplantation. The risk for viral infection is a function of the specific virus encountered and the intensity of immune suppression used to prevent graft rejection ...
Sahar A. Shams-aldein   +4 more
doaj   +4 more sources

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