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Epstein–Barr virus (EBV) infection in infancy
Journal of Clinical Virology, 2001Epstein-Barr virus (EBV) has been shown to be the cause of infectious mononucleosis (IM) and has more complicated associations with several malignant diseases. These EBV associated diseases provide a strong incentive for the development of an EBV vaccine. Most primary EBV infection during infancy and early childhood is mild or subclinical.
Chan, KH +4 more
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Chronicity of Epstein-Barr Virus Infection
Annals of Internal Medicine, 1985Excerpt Multiple lines of investigation using serologic, virologic, and immunologic techniques have solidly established that infectious mononucleosis results from a primary infection with Epstein-B...
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Serum epstein–barr virus DNA load in primary epstein–barr virus infection
Journal of Medical Virology, 2004AbstractSpecific viral laboratory diagnosis of primary Epstein–Barr Virus (EBV) infection is usually based on antibody‐detection assays. During acute, lytic phase of infection, viral DNA can also be detected in serum. In the present study, the diagnostic utility of EBV DNA detection and quantitation in serum in primary EBV infection was investigated ...
Claudia C, Bauer +5 more
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The ABC of Epstein-Barr Virus Infections
2007The EBV has evolved mechanisms that allow it to take advantages of different aspects of the human immune system, resulting in evasion of the defense mechanisms of the host. The virus is capable of resting calmly in a "sea of tranquility". The virus has the unique ability among herpesviruses to transform infected B lymphocytes, thereby creating the ...
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Diagnostic Testing in Epstein-Barr Virus Infection
Clinical Chemistry and Laboratory Medicine, 2001Laboratory diagnosis of Epstein-Barr virus (EBV) infection is improving with the development of new technologies. Quantification of the virus by real-time polymerase chain reaction (PCR) and evaluation of EBV-specific T cells, especially by tetrameric human leukocyte antigens, are noteworthy candidates for monitoring procedures in clinical laboratories
T, Kudo +5 more
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Epstein-Barr virus infection and human malignancies
International Journal of Experimental Pathology, 2001The Epstein-Barr virus (EBV) is a herpes virus which establishes a life-long persistent infection in over 90% of the human adult population world-wide. Based on its association with a variety of lymphoid and epithelial malignancies, EBV has been classified as a group 1 carcinogen by the International Agency for Research on Cancer.
G, Niedobitek, N, Meru, H J, Delecluse
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Persistent Epstein-Barr Virus Infection and Pregnancy
Journal of Infectious Diseases, 1983Women seropositive for Epstein-Barr virus (EBV) were studied during pregnancy for reactivation of latent, persistent infection. Individual women usually (94%) maintained constant titers of antibodies to EBV-specific antigens, including viral capsid antigen, early antigen, and EBV-associated nuclear antigen.
G, Fleisher, R, Bolognese
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Molecular diagnosis of Epstein–Barr virus infections
Expert Opinion on Medical Diagnostics, 2008Epstein-Barr virus (EBV) is an ubiquitous virus infecting the majority of people worldwide. Primary infection is usually sub clinical, except in a number of cases when it causes infectious mononucleosis. This diagnosis is usually based on serology, however, this may not always be conclusive.
Steven Ft, Thijsen, Marjolein Pd, Deege
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The Epstein-Barr virus and EB virus infections in childhood
The Journal of Pediatrics, 1979A DECADE has passed since the Epstein-Barr virus was shown to be the etiologic agent of heterophile-positive infectious mononucleosis. In the intervening ten years much attention has been focused on the pathogenesis of the disease, the unique biologic characteristics of the virus, the epidemiology of EBV infection in various parts of the world, and the
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Cimetidine, Ranitidine, and Epstein-Barr Virus Infection
Annals of Internal Medicine, 1986Excerpt To the editor: Patients with chronic Epstein-Barr virus infection (1) might be relieved to have their syndrome diagnosed but are usually discouraged when told there is no recognized effecti...
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