Results 91 to 100 of about 6,458 (228)

Anoikis in cell fate, physiopathology, and therapeutic interventions

open access: yesMedComm, Volume 5, Issue 10, October 2024.
1. Anoikis is an integrin‐dependent form of apoptosis and can affect cell fate. 2. Anoikis widely exists in the physiological and pathological processes of life. 3. Anoikis‐based regulatory strategies are potential targets for therapeutic intervention.
Jie Mei   +12 more
wiley   +1 more source

The impact of antiplatelet and anticoagulant medications on early implant failure following sinus floor augmentation: A retrospective cohort analysis

open access: yesClinical Implant Dentistry and Related Research, Volume 26, Issue 5, Page 1046-1055, October 2024.
Abstract Introduction The effect of antiplatelet and anticoagulant medications on the outcomes of sinus floor augmentation remains unclear. Methods This retrospective cohort study analyzed data from electronic medical records of consecutive patients undergoing sinus floor augmentation at a single medical center.
Ehud Jonas   +5 more
wiley   +1 more source

Cibles des médicaments antithrombotiques [PDF]

open access: yes, 2006
Pour la quasi-totalité des classes thérapeutiques antithrombotiques actuellement utilisées et à venir, le ciblage a été initialement la conséquence d’une observation et non pas le fruit d’une recherche méthodique scientifique.
Drouet, Ludovic, Ripoll, Laurent
core   +1 more source

Platelet glycoprotein IIb/IIIa antagonists in ischemic stroke patients without endovascular therapy: A meta‐analysis

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 44, Issue 8, Page 675-691, August 2024.
Abstract Platelet glycoprotein (GP) IIb/IIIa antagonists have been employed in selective patients after endovascular therapy (EVT) for acute ischemic stroke (AIS), yet application in patients without EVT is debated. This meta‐analysis of randomized controlled studies on AIS patients without EVT assessed the effectiveness and safety of platelet GP IIb ...
Dongjun Xu   +7 more
wiley   +1 more source

Small molecule– and peptide–drug conjugates addressing integrins: A story of targeted cancer treatment

open access: yesJournal of Peptide Science, Volume 30, Issue 7, July 2024.
The development of highly affine, selective peptides and small molecules in recent years has allowed peptide drugs (PDCs) and small molecule–drug conjugates (SMDCs) to increasingly compete with antibody–drug conjugates (ADCs). This review summarises and describes integrin‐addressing PDCs and SMDCs, while highlighting points of great interest.
Jannik Paulus, Norbert Sewald
wiley   +1 more source

Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction [PDF]

open access: yes, 2017
Recent clinical data show that the risk of coronary thrombosis after antiplatelet drugs withdrawal is much higher than that of surgical bleeding if they are continued.
Chassot, P.-G   +2 more
core  

Investigation of interaction of human platelet membrane components with anticoagulant drugs Abciximab and Eptifibatide

open access: yesFolia Histochemica et Cytobiologica, 2010
Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications inacute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex ...
Ewa Gorodkiewicz   +2 more
doaj  

Platelet Inhibition in Percutaneous Coronary Interventions [PDF]

open access: yes, 2018
: Mechanical disruption of atherosclerotic plaques at the time of percutaneous coronary intervention (PCI) is a potent stimulus for arterial thrombosis.
Roffi, Marco, Wyss, Christophe
core  

Platelet Glycoprotein IIb/IIIa Receptor Inhibition in Non-ST-Elevation Acute Coronary Syndromes [PDF]

open access: yes, 1999
BACKGROUND: Glycoprotein (GP) IIb/IIIa receptor blockers prevent life-threatening cardiac complications in patients with acute coronary syndromes without ST-segment elevation and protect against thrombotic complications associated ...
Akkerhuis, K.M. (Martijn)   +5 more
core  

Bridging Experience With Eptifibatide After Stent Implantation

open access: yesCritical Pathways in Cardiology: A Journal of Evidence-Based Medicine, 2016
Background: Patients who have undergone intracoronary stent implantation often require surgery within the first year after the procedure. Planned or emergent surgical intervention requires interruption of antiplatelet therapy and is associated with an increased risk of stent thrombosis. Eptifibatide, an intravenous glycoprotein
Marie Gerhard-Herman   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy