The review presents literature data on the key role of platelet aggregation (PA) for intracoronary thrombogenesis in various acute coronary syndromes (ACS) and percutaneous coronary interventions (PCI).
T. A. Batyraliev +4 more
doaj
Systematic adjudication of myocardial infarction end-points in an international clinical trial
Background Clinical events committees (CEC) are used routinely to adjudicate suspected end-points in cardiovascular trials, but little information has been published about the various processes used.
Lee Kerry L +16 more
doaj +1 more source
Intracoronary Eptifibatide During Primary Percutaneous Coronary Intervention in Early Versus Late Presenters with ST Segment Elevation Myocardial Infarction: A Randomized Trial [PDF]
Ayman Elbadawi +9 more
openalex +1 more source
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction: A narrative review
This article reviews the major pharmacologic features of, and clinical evidence on, adjuvant medical therapy in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention.
Daniel Caldeira, Hélder Pereira
doaj +1 more source
Emerging drugs for sickle cell anemia. [PDF]
INTRODUCTION: The search for effective therapeutic interventions for sickle cell disease (SCD) has been an ongoing endeavor for over 50 years. During this period, only hydroxyurea (HU), which received US FDA approval in February 1998, was identified as ...
Ballas, Samir K., Singh, Priya C
core +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Eptifibatide and 7E3, but Not Tirofiban, Inhibit α v β 3 Integrin–Mediated Binding of Smooth Muscle Cells to Thrombospondin and Prothrombin [PDF]
Robert M. Scarborough
openalex +1 more source
Eptifibatide in Coronary Intervention [PDF]
Matthew W. Sherwood, James E. Tcheng
openalex +1 more source
Inhibition of platelet mediated arterial thrombosis and platelet granule exocytosis by 3'4'-dihydroxyflavonol and quercetin [PDF]
Flavonols are polyphenolic compounds with broad-spectrum kinase inhibitory, as well as potent anti-oxidant and anti-inflammatory properties. Anti-platelet potential of quercetin (Que) and several related flavonoids have been reported; however, few ...
Jackson, D +3 more
core

