Systematic adjudication of myocardial infarction end-points in an international clinical trial
Background Clinical events committees (CEC) are used routinely to adjudicate suspected end-points in cardiovascular trials, but little information has been published about the various processes used.
Lee Kerry L+16 more
doaj +1 more source
Platelet Function Monitoring in Patients With Coronary Artery Disease [PDF]
Studies focused on patient responsiveness to antiplatelet therapies, particularly aspirin and clopidogrel, have increased in recent years. However, the relations of in vivo platelet function and adverse clinical events to results of ex vivo platelet ...
Becker, Richard C.+4 more
core +1 more source
Cost-Effectiveness of Platelet Glycoprotein IIb/IIIa Inhibition With Eptifibatide in Patients With Non–ST-Elevation Acute Coronary Syndromes [PDF]
Daniel B. Mark+9 more
openalex +1 more source
Early Percutaneous Coronary Intervention, Platelet Inhibition With Eptifibatide, and Clinical Outcomes in Patients With Acute Coronary Syndromes [PDF]
Neal S. Kleiman+12 more
openalex +1 more source
Emerging drugs for sickle cell anemia. [PDF]
INTRODUCTION: The search for effective therapeutic interventions for sickle cell disease (SCD) has been an ongoing endeavor for over 50 years. During this period, only hydroxyurea (HU), which received US FDA approval in February 1998, was identified as ...
Ballas, Samir K., Singh, Priya C
core +1 more source
Eptifibatide and 7E3, but Not Tirofiban, Inhibit α v β 3 Integrin–Mediated Binding of Smooth Muscle Cells to Thrombospondin and Prothrombin [PDF]
Manjiri Lele+3 more
openalex +1 more source
Administration of abciximab to patients receiving tirofiban or eptifibatide: effect on platelet function [PDF]
Eli I. Lev+9 more
openalex +1 more source
Acute Coronary Syndromes: Management and Secondary Prevention [PDF]
Acute coronary syndromes represent a broad spectrum of ischemic myocardial events including unstable angina, non-ST elevation myocardial infarction and acute ST elevation myocardial infarction, which are associated with high morbidity and mortality. They
Wenaweser, Peter, Windecker, Stephan
core
Bleeding Associated with Eptifibatide Targeting Higher Risk Patients with Acute Coronary Syndromes: Incidence and Multivariate Risk Factors [PDF]
Saeed Rasty+2 more
openalex +1 more source
Increased Risk in Patients With High Platelet Aggregation Receiving Chronic Clopidogrel Therapy Undergoing Percutaneous Coronary Intervention Is the Current Antiplatelet Therapy Adequate? [PDF]
ObjectivesWe sought to determine whether patients receiving chronic clopidogrel therapy undergoing nonemergent stenting who display high on-treatment preprocedural platelet aggregation measured by standard light transmittance aggregometry and ...
Bassi, Ashwani K.+5 more
core +1 more source