Results 211 to 220 of about 127,286 (242)

Health Perceptions and HRQL With Soft-Tissue Sarcoma at 12 Months Post-Op: Using the Wilson-Cleary Model to Evaluate the Measurement Properties of the RNLI and EQ-5D-3L. [PDF]

J Surg Oncol
Andersen NJ, Bergeron C, Turcotte R, Körner A.   +3 more
europepmc   +1 more source

Extracellular Vesicle‐Encapsulated Small RNAs From Clostridium Butyricum Modulate Host Intestinal Lipid Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Extracellular vesicles (EVs) derived from C. butyricum can enter intestinal epithelial cells and mediate the anti‐lipid absorption effects by delivering miRNA‐like RNAs (milRNAs), particularly milRNA‐3020179, which primarily targeted host genes majorly including PPARα. Deletion of milRNA‐3020179 in C. butyricum abolished its effects on lipid deposition
Hong Hu, Yiwen He, Jing Liang, Qi Han, Xuqing Liang, Guangtian Cao, Yulong Tang, Liuqin He, Yulong Yin, Xihong Zhou   +9 more
wiley   +1 more source

Sacubitril/valsartan and quality of life assessed using the EuroQol Five-dimension Three-level questionnaire level sum score (EQ-5D-3L-LSS) in patients with HFrEF and HFmrEF/HFpEF. [PDF]

Eur Heart J Cardiovasc Pharmacother
Yang M, Henderson AD, Anand IS, Desai AS, Lam CSP, Maggioni AP, Martinez FA, Rouleau JL, Swedberg K, Vaduganathan M, van Veldhuisen DJ, Zannad F, Zile MR, Packer M, Rizkala A, Lewis EF, Jhund PS, Solomon SD, McMurray JJV.   +18 more
europepmc   +1 more source

Cost‐effectiveness analysis of total intravenous vs. inhalation anaesthesia among adults aged ≥ 50 y undergoing major non‐cardiac surgery

Anaesthesia, Volume 81, Issue 10, Page 1378-1385, October 2026.
Summary Introduction Total intravenous and inhalational anaesthesia are used widely to maintain general anaesthesia for major non‐cardiac surgery, yet their comparative cost‐effectiveness remains uncertain. The VITAL trial evaluated clinical outcomes, showing no difference in days alive and at home at 30 days.
Samuel Frempong, Rebecca Kandiyali, James Mason, Louise Hiller, Janet Dunn, Katie Booth, Ramani Moonesinghe, Rupert Pearse, Ben Shelley, Shaman Jhanji, Joyce Yeung, on behalf of the VITAL Trial Team   +11 more
wiley   +1 more source

Adjusting Health State Utility Values for Multiple Conditions: Real-World EQ-5D-3L Data Modeling in Brazil. [PDF]

Pharmacoecon Open
da Costa MR, Dos Santos Júnior B, da Silva Santos M.   +2 more
europepmc   +1 more source

Impact of Osilodrostat on Health‐Related Quality of Life in Cushing's Disease: Analysis of Patient‐Reported Outcomes From the Phase III LINC 3 and LINC 4 Clinical Trials

Clinical Endocrinology, Volume 105, Issue 4, Page 452-463, October 2026.
ABSTRACT Objective Evaluate the effects of osilodrostat short‐ and long‐term treatment on health‐related quality of life (HRQoL) in Cushing's disease. Design LINC 3 and LINC 4 studies (pooled analysis). Patients 185 patients (mean baseline total scores: Cushing's Quality of Life [CushingQoL], 44.0; Beck Depression Inventory II [BDI‐II], 15.6; EuroQol ...
John Newell‐Price, Beverly M. K. Biller, Maria Fleseriu, Beatrice Gueron, Grzegorz Binowski, Anna Paćkowska, Mônica R. Gadelha   +6 more
wiley   +1 more source

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Journal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman, David Ray, Andrew Farmer, Poppy C. E. Green, Victoria Harris, Fredrik Karpe, Colin A. Espie, Diana Mantripp, Thomas Marjot, Niall M. McGowan, Jeremy W. Tomlinson, Simon D. Kyle   +11 more
wiley   +1 more source

Health-Related Quality of Life due to malaria in the Brazilian Amazon using EQ-5D-3L. [PDF]

PLoS Negl Trop Dis
Andrade MV, de Souza Noronha KVM, Guedes GR, Julião NA, de Carvalho LR, de Souza A, Silva VA, Motta-Santos AS, Bracarense H, Peterka C, Castro MC.   +10 more
europepmc   +1 more source

Iterative Genome Engineering Platform Enables Efficient Sucrose Biosynthesis From CO2 in Photosynthetic Synechococcus elongatus UTEX 2973

Plant Biotechnology Journal, Volume 24, Issue 10, Page 5284-5299, October 2026.
ABSTRACT The single crossover occurring via homologous recombination is a common phenomenon existing among microbes like Escherichia coli, Bacillus subtilis, Vibrio natriegens, Gluconobacter oxydans and most cyanobacteria species, threatening the stability of engineered strains and challenging iterative genetic engineering. Among them, we take the fast‐
Shubin Li, Tao Sun, Dailin Liu, Tong Zhang, Lei Chen, Weiwen Zhang   +5 more
wiley   +1 more source