Results 111 to 120 of about 41,400 (238)

Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.

PLoS Genetics, 2008
Genome-wide gene expression profiling has been extensively used to generate biological hypotheses based on differential expression. Recently, many studies have used microarrays to measure gene expression levels across genetic mapping populations.
Chunlei Wu, David L Delano, Nico Mitro, Stephen V Su, Jeff Janes, Phillip McClurg, Serge Batalov, Genevieve L Welch, Jie Zhang, Anthony P Orth, John R Walker, Richard J Glynne, Michael P Cooke, Joseph S Takahashi, Kazuhiro Shimomura, Akira Kohsaka, Joseph Bass, Enrique Saez, Tim Wiltshire, Andrew I Su   +19 more
doaj   +1 more source

Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients

, 2021
Huijie Lu, Haixia Jiang, Siyao Yang, Chengcheng Li, Chuanjiang Li, Ruifan Shao, Pai Zhang, Daoyi Wang, Zhiwei Liu, Huana Qi, Yinuan Cai, Wenbin Xu, Xiaojie Bao, Hailan Wang, Liang Li   +14 more
openalex   +1 more source

Bayesian Genome-wide TWAS method to leverage both cis- and trans- eQTL information through summary statistics [PDF]

, 2020
Justin M. Luningham, Junyu Chen, Shizhen Tang, Philip L. De Jager, David A. Bennett, Aron S. Buchman, Jingjing Yang   +6 more
openalex   +1 more source

Leveraging Genetic Instrumental Variables and Sequencing Analysis to Identify a Prognostic Signature Based on Epithelial Cell Markers in Lung Adenocarcinoma

Thoracic Cancer, Volume 17, Issue 1, January 2026.
It begins with the identification of malignant AT2 cells, progresses through pseudo‐time analysis and Mendelian randomization to identify prognostic genes, and leads into the construction and validation of the prognostic signature. The visual story also includes functional exploration through Gene Ontology enrichment analysis and protein–protein ...
Jiaye Lao, Ziqing Han, Xinjing Lou, Jinxuan Ye, Chen Gao, Linyu Wu   +5 more
wiley   +1 more source

Additional file 1 of Genome-wide analysis of expression QTL (eQTL) and allele-specific expression (ASE) in pig muscle identifies candidate genes for meat quality traits

, 2020
Yan Liu, Xiaolei Liu, Zhiwei Zheng, Tingting Ma, Ying Liu, Huan Long, Huijun Cheng, Ming Fang, Jing Gong, Xinyun Li, Shuhong Zhao, Xuewen Xu   +11 more
openalex   +1 more source

TreeQTL: hierarchical error control for eQTL findings [PDF]

, 2015
Christine B. Peterson, Marina Bogomolov, Yoav Benjamini, Chiara Sabatti   +3 more
openalex   +1 more source

Mitochondrial DNA Variation in the Aging Human Cerebral Cortex and Cerebellum

Aging Cell, Volume 25, Issue 1, January 2026.
We used cerebellum and frontal cortex whole genome sequencing data from the North American Brain Expression Consortium to investigate mitochondrial DNA deletions, single nucleotide variants, and copy number. We found significant differences between brain regions and age effects for all these metrics, which illustrate mitochondrial changes in healthy ...
Audrey A. Omidsalar, David R. Tyrpak, J. Andrew MacKay, Kelvin Yen, Pinchas Cohen, Geidy Serrano, Thomas G. Beach, Michael A. Nalls, Dena G. Hernandez, Mark R. Cookson, Andrew B. Singleton, J. Raphael Gibbs, North American Brain Expression Consortium, Brooke E. Hjelm   +13 more
wiley   +1 more source

Joint analyses of multi-tissue Hi-C and eQTL data demonstrate close spatial proximity between eQTLs and their target genes [PDF]

, 2019
Jingting Yu, Ming Hu, Chun Li
openalex   +1 more source

Prioritizing candidate eQTL causal genes in Arabidopsis using RANDOM FORESTS [PDF]

, 2022
Margi Hartanto, Asif Ahmed Sami, Dick de Ridder, Harm Nijveen   +3 more
openalex   +1 more source

The PbrMADS1–PbrMYB169 complex has uniquely emerged to regulate lignification of stone cells in pear

Journal of Integrative Plant Biology, Volume 68, Issue 1, Page 239-256, January 2026.
Genome‐wide association study in pear identified a SEP3‐subfamily transcription factor, PbrMADS1, which interacts with PbrMYB169 to regulate stone cell lignification. The methionine at position 63 in PbrMADS1 was essential for this interaction. This amino acid variation may underlie the functional divergence of homologous SEP3 genes among Rosaceae ...
Yongsong Xue, Shulin Chen, Yingyu Hao, Meng Shan, Pengfei Zheng, Runze Wang, Mingyue Zhang, Jun Wu, Cheng Xue   +8 more
wiley   +1 more source