Results 61 to 70 of about 7,183,175 (247)

A First Look on the New Halle Economic Projection Model [PDF]

open access: yes
In this paper we develop a small open economy model explaining the joint determination of output, inflation, interest rates, unemployment and the exchange rate in a multi-country framework.
Oliver Holtemöller   +3 more
core  

Prediction of Machining Deformation for Split Equal-Base Circle Bevel Gear

open access: yesApplied Sciences
Given the deformation issues in machining segmented equal-base bevel gears, this paper investigates the variations of additional stress during the machining process, considering the gear blank material, residual internal stress, and gear blank design.
Kai Xu   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Polyazimuthal Map Projections

open access: yesKartografija i Geoinformacije, 2019
A polyazimuthal map projection is a mapping that represents parallels as non-concentric full circles on the plane. Polyazimuthal mappings are almost never mentioned in the literature dealing with map projections.
Krisztián Kerkovits
doaj  

A GIS-based reassessment of the cartographic accuracy of the Huang Yu Quan Lan Tu and the Nei Fu Yu Tu

open access: yesAnnals of GIS
This study systematically evaluates the cartographic accuracy of the Qing Dynasty’s Huang Yu Quan Lan Tu (Kangxi Map) and Nei Fu Yu Tu (Qianlong Map), using 26 lakes in the southern Mongolian Plateau as natural references.
Nashun Dalai   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Williamsburg Area Bicyclists Records

open access: yes, 2006
Primarily issues of the newsletter of the Williamsburg Area Bicyclists, "The Flying Wheel," dated from July 2006 to May 2007. There is also artwork, recurring advertisements, and information on the production of the newsletter.
Williamsburg Area Bicyclists
core  

VERTICAL PROJECTION EFFICIENCY OF PIVOT POINTS USING ELECTRONIC TACHEOMETER DURING CONSTRUCTION OF BUILDINGS AND STRUCTURES

open access: yesНаука и техника, 2014
The paper shows that functional limitation of zenith devices and introduction of modern high-accuracy electronic tacheometers should lead to substitution of the mentioned devices for tacheometers in geodesic works concerning vertical projection of pivot ...
M. S. Nesterenok   +2 more
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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