Results 41 to 50 of about 7,183,175 (247)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Regulasi Penyerahan Lokal Konten Universitas Medan Area
17 HalamanLokal konten adalah karya yang dihasilkan oleh suatu institusi yang sifatnya ilmiah dan siap untuk di publikasi. Lokal konten Universitas Medan Area adalah karya-karya ilmiah yang dihasilkan oleh dosen dan mahasiswa serta lembaga/unit yang ada ...
Universitas Medan Area, Perpustakaan
core +1 more source
Airy criterion and the ideal mapping of an ellipsoid of revolution onto a sphere
This paper addresses the problem of constructing an ideal projection of an ellipsoid of revolution onto a sphere based on the Airy criterion. General equations required to solve the problem are derived. In particular, the Euler–Urmaev system is obtained,
Elena Novikova
doaj +1 more source
Introduction Collimation of the primary beam is an important factor in radiography to reduce dose and improve image quality. The introduction of larger detector plates in direct digital radiography (DR) allows the exposed area to be calculated by ...
Sally Ball +2 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
If we take a distance from a map without considering the distortion, we will not get the correct value. We will get the correct value if we take the distortion into account, that is, if we use an expression for distance that does not contain distortion ...
Miljenko Lapaine
doaj +1 more source

