Results 121 to 130 of about 390,754 (252)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
How does sports participation influence individual gender attitudes? An empirical study based on CGSS data. [PDF]
Front PsycholZhai J, Liu D, Wang Z.
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The health and care workforce crisis: co-benefits of gender-transformative approaches and capacities for implementation. [PDF]
Eur J Public HealthKuhlmann E +4 more
europepmc +1 more source
Equal Pay for Equal Work with Reference to Gender Equality
Equal pay for equal work mandates equal pay for individuals that do the same type of work. It is enshrined in international instruments like the ILO Constitution, Equal Remuneration Convention, UDHR, CEDAW, etc. and in Article 39(d) of the Indian Constitution. It is most commonly applicable in the context of gender-based discrimination in pay—work of a
openaire +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Changes in life expectancy and life span equality during the COVID-19 epidemic in 2020-22 in Japan. [PDF]
PLoS OneOkada Y, Nishiura H.
europepmc +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Conceptualising equity in basic medical education accreditation standards: A qualitative study of expert perspectives. [PDF]
Pak J Med SciShaheen N, Mahboob U, Sethi A, Irfan M.
europepmc +1 more source