Results 51 to 60 of about 524,830 (267)

Welcome to the fertility clinic of the future! Using speculative design to explore the moral landscape of reproductive technologies

open access: yesHumanities & Social Sciences Communications, 2023
The evolving field of reproductive technologies greatly alters our practices of conception and pregnancy. It is thus crucial to develop such innovations in a democratic and sustainable manner through public participation.
W. Willems   +4 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Factors affecting the size of female labour force in Malta [PDF]

open access: yes, 2006
Malta's female labour supply increased substantially over the last two decades. However, female participation in Malta remains much lower than that of males and is also the lowest compared to other EU countries.
Caruana, Kevin
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

L’orientation des filles vers des métiers non traditionnels en sciences et en technologies

open access: yesRevue Interventions Économiques, 2009
The struggle for equality between men and women has appeared in every social field, including those of education and work. In this struggle, one of the strategies adopted by the feminist movement and by the governments of many countries has been to ...
Geneviève Szczepanik   +2 more
doaj   +1 more source

Participation of women in the health workforce in the fragile and conflict-affected countries: a scoping review

open access: yesHuman Resources for Health, 2021
Introduction and background The full participation of women as healthcare providers is recognized globally as critical to favorable outcomes at all levels, including the healthcare system, to achieving universal health coverage and sustainable ...
Basnama Ayaz   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Activating the family? Moral economy and post-industrial family policy

open access: yesCulture, Practice & Europeanization
Expanding on the concept of the moral economy, the article investigates implicit justice assumptions connected to family policies in post-industrial European welfare states.
Laura Lüth
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

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