Results 81 to 90 of about 6,568,759 (295)

Some clarifications about the Bohmian geodesic deviation equation and Raychaudhuri's equation

open access: yes, 2017
One of the important and famous topics in general theory of relativity and gravitation is the problem of geodesic deviation and its related singularity theorems.
Golshani, Mehdi, Rahmani, Faramarz
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Effects of correction equation for actual sodium concentration on the reduction in frequency of reports on pseudohyponatremia

open access: yesJournal of Laboratory Medicine, 2020
Serum sodium concentration could be spuriously reduced by excess glucose or lipid; thus, hyponatremia should be reassessed before reporting in order to exclude the possibility of pseudohyponatremia.
Cho Jooyoung, Uh Young, Choi Seong Jin
doaj   +1 more source

Spinor with Schr\" odinger symmetry and non-relativistic supersymmetry

open access: yes, 2011
We construct the $d$ dimensional "half" Schr\"odinger equation, which is a kind of the root of the Schr\"odinger equation, from the $d+1$ dimensional free Dirac equation.
Nojiri, Shin'ichi, Yoda, Hiroshi
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Electromagnetic Coupling in Kemmer-Duffin-Petiau Theory

open access: yes, 1998
We analyse the electromagnetic coupling in the Kemmer-Duffin-Petiau (KDP) equation. Since the KDP--equation which describes spin-0 and spin-1 bosons is of Dirac-type, we examine some analogies and differences from the Dirac equation.
Akhiezer   +21 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Higher-order corrections to the short-pulse equation

open access: yes, 2012
Using renormalization group techniques, we derive an extended short- pulse equation as approximation to a nonlinear wave equation. We investigate the new equation numerically and show that the new equation captures efficiently higher- order effects on ...
Agrawal G P   +12 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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