Results 121 to 130 of about 4,215,064 (363)
The Atmosphere of a Black Hole
, 2016 We present a static, isotropic fluid solution around a black hole and its effects on the field equations and the horizon. We offer the solutions, their descriptions and we comment on their shortcomings. We derive from the proposed metric the density, the
Arik, Metin, Senikoglu, Yorgo
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Equation of state of HE detonation products
EPJ Web of Conferences, 2011 Computational analysis of steady-state HE detonation parameters is possible if one knows the equation of state of detonation products and thermal energy released at the Jouget point during detonation.
Nadykto B.A.
doaj +1 more source
Non-Radial Oscillation Modes of Superfluid Neutron Stars Modeled with CompOSE
Universe, 2018 We compute the principal non-radial oscillation mode frequencies of Neutron Stars described with a Skyrme-like Equation of State (EoS), taking into account the possibility of neutron and proton superfluidity.
Prashanth Jaikumar +2 more
doaj +1 more source
Determination of the Equation of State of Dense Matter
, 2002 Nuclear collisions can compress nuclear matter to densities achieved within neutron stars and within core-collapse supernovae. These dense states of matter exist momentarily before expanding.
Danielewicz, P., Lacey, R., Lynch, W. G.
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2019 From a general point of view, the equation of state and the change in thermophysical properties of Nb nanocrystals along 300 K and 3000 K isotherms with increasing pressure were calculated on the basis of the Mie – Lennard – Jones pair interatomic ...
S.P. Kramynin
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source