Results 121 to 130 of about 4,107,153 (300)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source

Quark matter equation of state and stellar properties

, 2012
In this paper we study strange matter by investigating the stability window within the QMDD model at zero temperature and check that it can explain the very massive pulsar recently detected.
Menezes, D. P., Torres, J. R.
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The Atmosphere of a Black Hole

, 2016
We present a static, isotropic fluid solution around a black hole and its effects on the field equations and the horizon. We offer the solutions, their descriptions and we comment on their shortcomings. We derive from the proposed metric the density, the
Arik, Metin, Senikoglu, Yorgo
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Thermodynamic Property Model of Wide-Fluid Phase Propane [PDF]

ITB Journal of Engineering Science, 2007
A new thermodynamic property model for propane is expressed in form of the Helmholtz free energy function. It consists of eight terms of the ideal-gas part and eighteen terms of the residual part.
I Made Astina, Juristiawan Firmansyah
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Multi-Component-Multiphase Flash Calculations for Systems Containing Gas Hydrates by Direct Minimization of Gibbs Free Energy [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2006
The Michelsen stability and multiphase flash calculation by direct minimization of Gibbs free energy of the system at constant temperature and pressure, was used for systems containing gas hydrates. The solid hydrate phase was treated as a solid solution.
Amir Abbas Izadpanah, Mohsen Vafaie Sefti, Farshad Varaminian   +2 more
doaj  

THERMODYNAMIC PROPERTIES OF ROCK-FORMING OXIDES, α-Al2O3, Cr2O3, α-Fe2O3, AND Fe3O4 AT HIGH TEMPERATURES AND PRESSURES

Геодинамика и тектонофизика, 2016
Equations of state of corundum (α-Al2O3), eskolaite (Cr2O3), hematite (α-Fe2O3), and magnetite (Fe3O4) are constructed based on the Helmholtz free energy by simultaneous optimization of ultrasonic, X-ray diffraction, dilatometric, and thermochemical ...
P. I. Dorogokupets, T. S. Sokolova, A. M. Dymshits, K. D. Litasov   +3 more
doaj   +1 more source