Results 81 to 90 of about 12,316,772 (314)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

On the control of an evolutionary equilibrium in micromagnetics [PDF]

open access: yes, 2006
Optimal control of magnetization in a ferromagnet is formulated as a mathematical program with evolutionary equilibrium constraints. To this purpose, we construct an evolutionary infinite-dimensional model which is discretized both in the space as well as in time variables.
Michal Kočvara   +2 more
openaire   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Equilibrium Corporate Finance [PDF]

open access: yes
We study a general equilibrium model with production where financial markets are incomplete. At a competitive equilibrium firms take their production and financial decisions so as to maximize their value.
Alberto Bisin   +2 more
core  

User equilibrium, system optimum, and externalities in time-dependent road networks [PDF]

open access: yes, 2007
This paper develops a comprehensive framework for analysing and calculating user equilibrium, system optimum, and externalities in time-dependent road networks.
Chow, A.H.F.
core  

Equilibrium transition study for a hybrid MAV [PDF]

open access: yes, 2011
Wind tunnel testing was performed on a VTOL aircraft in order to characterize longitudinal flight behavior during an equilibrium transition between vertical and horizontal flight modes.
Moschetta, Jean-Marc   +7 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Optimal adaptive pinning control of network systems onto an unstable equilibrium

open access: yes
When controlling network systems through pinning, distributed adaptive strategies have been devised to increase the coupling and control gains until convergence onto the desired equilibrium configuration is attained.
Calabrese, Carmela   +3 more
core   +1 more source

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