Results 31 to 40 of about 10,252,023 (301)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Equilibrium mechanics of monolayered epithelium [PDF]
Journal of Theoretical Biology, 2009 In order to fully understand the epithelial mechanics it is essential to integrate different levels of epithelial organization. In this work, we propose a theoretical approach for connecting the macroscopic mechanical properties of a monolayered epithelium to the mechanical properties at the cellular level.
Derganc, Jure +2 more
openaire +4 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A Cost-Optimized Resource Provisioning Policy for Heterogeneous Cloud Environments
IEEE Access, 2017 To avoid the drawbacks of a pricing mechanism in heterogeneous cloud environments that considers only single resources, we propose a multi-resource combinatorial pricing mechanism in this paper.
Xin Chen +4 more
doaj +1 more source
Mathematics, 2022 Extreme multistability has frequently been reported in autonomous circuits involving memory-circuit elements, since these circuits possess line/plane equilibrium sets. However, this special phenomenon has rarely been discovered in non-autonomous circuits.
Bei Chen +4 more
doaj +1 more source
Kinetics in Mg-based hydrogen storage materials: Enhancement and mechanism
Journal of Magnesium and Alloys, 2019 Mg-based materials have been intensively studied for hydrogen storage applications due to their high energy density up to 2600 Wh/kg or 3700 Wh/L. However, the Mg-based materials with poor kinetics and the necessity for a high temperature to achieve 0.1 ...
Qun Luo +5 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2012 Reactive oxygen species (ROS) are produced as a normal product of plant cellular metabolism. Various environmental stresses lead to excessive production of ROS causing progressive oxidative damage and ultimately cell death.
Pallavi Sharma +3 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
On the Concept of Equilibrium in Sanctions and Countersanctions in a Differential Game
Mathematics, 2023 This paper develops the methodology for modeling decision processes in complex controlled dynamic systems. The idea of balancing such systems (driving them to equilibrium) is implemented, and a new mechanism for the equilibria’s stability is proposed ...
Vladislav I. Zhukovskiy +1 more
doaj +1 more source