Results 71 to 80 of about 5,589,661 (305)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Advances in Difference Equations, 2017 In this paper, we consider a nonlinear non-differentiable dynamic system in microbial continuous cultures involving all possible metabolic pathways of the inhibition mechanisms of 3-hydroxypropionaldehyde onto the cell growth and the transport systems of
Jiajia Lv, Liping Pang, Enmin Feng
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On generalized equilibrium points
Journal of Mathematical Analysis and Applications, 2004 Let \(X=X_{1}\times X_{2}\times\cdots\times X_{n}\) be a product of Euclidean spaces and \(\varphi:X\times X\rightarrow\mathbb{R}\) be a function. This paper introduces the notion of \(\varepsilon\)-equilibrium point of \(f\), where \(\varepsilon=(\varepsilon_{1},\varepsilon_{2},\ldots\varepsilon_{n} )\in\mathbb{R}^{n}\), as follows: \(x=(x_{1},x_{2 ...
Kas, P, Kassay, G, Sensoy, ZB
openaire +1 more source
Fall back equilibrium is a refinement of the Nash equilibrium concept. In the underly- ing thought experiment each player faces the possibility that, after all players decided on their action, his chosen action turns out to be blocked.
Borm, P.E.M. +2 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
ModellingThis paper presents a novel four-dimensional autonomous conservative model characterized by an infinite set of equilibrium points and an unusual algebraic structure in which all eigenvalues of the Jacobian matrix are zero.
Surma H. Ibrahim +2 more
doaj +1 more source
Central Point Notice of Adopted Amendment (2008-12-29) [PDF]
, 2008 162 pp. Adopted 2008-12-29. Department of Land Conservation and Development Notice of Adopted AmendmentThe attached proposed amendment is the Central Point Transportation System Plan (TSP) which will be an element of the updated Central Point ...
Central Point (Or.)
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
AxiomsThe concept of fuzzy modeling and fuzzy system design has opened new horizons of research in functional analysis, having a significant impact on major fields such as data science, machine learning, and so on.
Sara Saud +4 more
doaj +1 more source