Results 91 to 100 of about 5,765,838 (310)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Approximate social nash equilibria and applications [PDF]

open access: yes
In this paper, a concept of approximate social Nash equilibria is considered and an existence result is given when the strategic spaces of the players are not compact. These have been obtained using an approximate fixed point theorem.
Vincenzo Scalzo
core  

Multiple time scales method for a two dimensional system with distributed delays

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science
Building on the simplified mathematical model derived from the dynamics of the hypothalamic-pituitary-adrenal (HPA) axis, which describes the interactions between ACTH and cortisol through a system of differential equations with distributed delays, this ...
Matei Maria Roxana
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Uniqueness Conditions for Point-Rationalizable [PDF]

open access: yes
The unique point-rationalizable solution of a game is the unique Nash equilibrium. However, this solution has the additional advantage that it can be justified by the epistemic assumption that it is Common Knowledge of the players that only best ...
Zimper, Alexander
core  

Annual report 2001/2002 - Pavee Point [PDF]

open access: yes, 2003
Pavee Point ...
Pavee Point Travellers Centre
core  

Novel adaptive generalized principal component analysis algorithm based on Hebbian rule

open access: yesTongxin xuebao, 2020
In order to adaptively estimate the generalized principal component from input signals,a novel generalized principal component analysis algorithm was proposed based on the Hebbian linear neuron model.Since the autocorrelation matrices of the signals were
Yingbin GAO   +3 more
doaj  

Equilibrium points in n -person games [PDF]

open access: yesProceedings of the National Academy of Sciences, 1950
Soit un jeu à de \(n\) personnes, où chaque joueur possède un systeme fini de stratégies pures. Chacun d'entre eux ayant choisi une tactique de jeu, l'ensemble de ces tactiques constitute un \(n\)-uple de stratégies pures. A tout \(n\)-uple correspond un système défini de paiement entre les partenaires. L'A. considère chacun de ces \(n\)-uples comme un
openaire   +3 more sources

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