Results 41 to 50 of about 5,589,661 (305)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Analisis dan Strategi Pengendalian Model Matematika Interaksi Sel Kanker Leukemia Mielositik Kronis dan Sel Imunitas

open access: yesContemporary Mathematics and Applications (ConMathA), 2020
Leukemia is a disease in the classification of cancer in the blood that is characterized by abnormal growth of blood cells in the bone marrow or lymphoid tissue, and generally occurs in leukocytes or white blood cells.
Nanda Amalia Rahma   +2 more
doaj   +1 more source

Dynamics and Bifurcation Analysis of an Eco-Epidemiological Model in a Crowley–Martin Functional Response with the Impact of Fear

open access: yesEngineering Proceedings, 2023
This article describes a three-species food web model that was developed by considering the interaction between susceptible prey, infected prey, and predator species.
Manickasundaram Siva Pradeep   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

PEMODELAN MATEMATIKA PADA EPIDEMI INFLUENZA DENGAN STRATEGI VAKSINASI

open access: yesJurnal MIPA, 2016
Pada tahun 2009 merebak epidemi flu burung kemudian diikuti epidemi flu babi. Epidemi flu tersebut menyebabkan beberapa kasus kematian dan banyak manusia yang masuk ke rumah sakit.
M Kharis, AN Cahyono
doaj  

Dynamics and Event-Triggered Impulsive Control of a Fractional-Order Epidemic Model with Time Delay

open access: yesFractal and Fractional, 2023
Due to the lack of timely protection measures against infectious diseases, or based on the particularity of the transmission of some infectious diseases and the time-varying connections between people, the transmission dynamics of infectious diseases in ...
Na Liu, Jia Wang, Qixun Lan, Wei Deng
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Adaptive Threshold Generation for Fault Detection with High Dependability for Cyber-Physical Systems

open access: yesApplied Sciences, 2018
Cyber-physical systems (CPS) applied to safety-critical or mission-critical domains require high dependability including safety, security, and reliability.
Youngmi Baek, Minsu Jo
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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