Results 111 to 120 of about 5,589,661 (305)

Central Point Notice of Adopted Amendment (2008-10-20)

, 2008
40 pp. Adopted 2008-10-20. Department of Land Conservation and Development Notice of Adopted AmendmentThe proposed amendment is the City of Central Point Buildable Lands Inventory (BLI) which will be a component of the updated Land Use Element of the ...
Central Point (Or.)
core  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Strategic plan: a framework for projected activities 2001-2005 / Pavee Point

, 2001
Pavee Point ...
Pavee Point Travellers Centre
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Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Design and Analysis of a New Four-Dimensional Chaotic System: Study of Dynamical Properties and Chaos Verification

Proceedings of the International Conference on Applied Innovations in IT
Presented a new (4D) four-dimensional hyperchaotic system with four nonlinear terms and thirteen positive parameters. The chaotic system is tested through Mathematica was used to confirm the results and prove that the system is super chaotic the complex ...
Zainab Ali Dheyab, Sadiq AbdulAziz Mehdi
doaj   +1 more source

AN INTERIOR-POINT METHOD FOR MPECs BASED ON STRICTLY FEASIBLE RELAXATIONS. [PDF]

An interior-point method for solving mathematical programs with equilibrium constraints (MPECs) is proposed. At each iteration of the algorithm, a single primaldual step is computed from each subproblem of a sequence.
Michael P. Friedlander, Francisco J. Nogales, Angel Víctor de Miguel, Stefan Scholtes   +3 more
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Analysis of Diabetes Complications Model With Time Delays

Cumhuriyet Science Journal
In this article, diabetes, a disease known to be influenced by genetic and environmental factors, is divided into two types: diabetes without complications (D) and diabetes with complications (C).
Mehmet Merdan, Şeyma Şişman
doaj   +1 more source