Games with Equilibrium Points [PDF]
Proceedings of the National Academy of Sciences, 1953 Otter, Richard, Dunne, John
openaire +3 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Assisting Forearm Function in Children With Movement Disorders via A Soft Wearable Robot With Equilibrium-Point Control. [PDF]
Front Robot AI, 2022 Realmuto J, Sanger TD.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Sensitivity and Stability Analysis of a SEIR Epidemic Model with Information
Journal of Experimental Life Science, 2019 In this paper, the construction and stability analysis of a SEIR epidemic model with information are discussed. This model contains information about how to prevent the spread of infectious diseases which is transmitted by infected individuals to ...
Robiatul Witari Wilda +2 more
doaj +1 more source
Analysis on the dynamic evolution of the equilibrium point of "carbon emission penetration" for energy-intensive industries in China: based on a factor-driven perspective. [PDF]
Environ Sci Pollut Res Int, 2023 Liu J, Wei D.
europepmc +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Multiple time scales method for a two dimensional system with distributed delays
Annals of the West University of Timisoara: Mathematics and Computer ScienceBuilding on the simplified mathematical model derived from the dynamics of the hypothalamic-pituitary-adrenal (HPA) axis, which describes the interactions between ACTH and cortisol through a system of differential equations with distributed delays, this ...
Matei Maria Roxana
doaj +1 more source