Results 51 to 60 of about 5,765,838 (310)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Adaptive Threshold Generation for Fault Detection with High Dependability for Cyber-Physical Systems
Applied Sciences, 2018 Cyber-physical systems (CPS) applied to safety-critical or mission-critical domains require high dependability including safety, security, and reliability.
Youngmi Baek, Minsu Jo
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Susceptible-Infected-Susceptible Epidemic Discrete Dynamic System Based on Tsallis Entropy
Entropy, 2020 This investigation deals with a discrete dynamic system of susceptible-infected-susceptible epidemic (SISE) using the Tsallis entropy. We investigate the positive and maximal solutions of the system. Stability and equilibrium are studied. Moreover, based
Shaher Momani +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Fractal and Fractional, 2020 In this work, a fractional predator-prey model with the harvesting rate is considered. Besides the existence and uniqueness of the solution to the model, local stability and global stability are experienced.
Mehmet Yavuz, Ndolane Sene
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Stability analysis in generalist predator-prey dynamics with predator harvesting [PDF]
Computational Ecology and SoftwareThis paper seeks to explore the stability assessment of a generalist predator-prey system with predator harvesting. The study presents a model examining the dynamics between primary prey and predator, considering the existence of a generalist predator ...
S. Vijaya, S. Ganga
doaj
Fundamentals of Synthesized Optimal Control
Mathematics, 2020 This paper presents a new formulation of the optimal control problem with uncertainty, in which an additive bounded function is considered as uncertainty.
Askhat Diveev +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source