Results 51 to 60 of about 2,343,490 (291)

THEORETICAL RESEARCH ON THE MULTI-CHANNEL REACTION MECHANISM AND KINETICS OF HNCS WITH OH-

open access: yesQuímica Nova
We presented a theoretical study on the detailed reaction mechanism and kinetics of the HNCS molecule with the OH-. The barrierless minimum energy path and the most favorable entrance channel have been determined by study the thermodynamic and kinetic ...
Li-Jie Hou   +4 more
doaj   +1 more source

Equilibrium Refinement through Negotiation in Binary Voting [PDF]

open access: yes, 2014
We study voting games on binary issues, where voters hold an objective over the outcome of the collective decision and are allowed, before the vote takes place, to negotiate their voting strategy with the other participants. We analyse the voters' rational behaviour in the resulting two-phase game, showing under what conditions undesirable equilibria ...
Grandi, Umberto   +2 more
openaire   +6 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Equilibrium refinement in finite action evidence games

open access: yesInternational Journal of Game Theory, 2023
AbstractEvidence games study situations where a sender persuades a receiver by selectively disclosing hard evidence about an unknown state of the world. Evidence games often have multiple equilibria. Hart et al. (Am Econ Rev 107:690-713, 2017) propose to focus on truth-leaning equilibria, i.e., perfect Bayesian equilibria where the sender discloses ...
openaire   +6 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Modeling the Solar Transition Region: Effects of Spatial Resolution on the Atmospheric Structure, Emission and Non-equilibrium Ionization

open access: yesThe Astrophysical Journal
The solar transition region (TR) is a narrow interface between the chromosphere and corona, where emitted radiation contains critical information pertinent to coronal heating processes.
Takuma Matsumoto
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Political cycles and policy convergence

open access: yesEconómica, 1998
This paper presents a model of elections with heterogeneous voters and asymmetric information about the incumbent's type, in which signaling in electoral years leads to policy convergence.
Eduardo Levy Yeyati
doaj  

Recombination Rates for 5fN Uranium Ions Using the Analogous 4f4 Nd III as a Guideline and Their Effect on Kilonova Nebular Spectra

open access: yesThe Astrophysical Journal
Dielectronic recombination (DR) is expected to be the dominant recombination process during the non–local thermodynamic equilibrium (NLTE) phase of kilonovae, yet reliable DR data remain unavailable for most heavy ions.
Niamh Ferguson   +4 more
doaj   +1 more source

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