Results 61 to 70 of about 2,466,570 (322)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

5G Cellular User Equipment: From Theory to Practical Hardware Design [PDF]

open access: yesIEEE Access, 2017
Research and development on the next generation wireless systems, namely 5G, has experienced explosive growth in recent years. In the physical layer, the massive multiple-input-multiple-output (MIMO) technique and the use of high GHz frequency bands are ...
Yiming Huo, Xiaodai Dong, W. Xu
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

MODELING OF PROCESSES OF REPAIR OF ENERGY EQUIPMENT

open access: yesВестник университета, 2019
In the article the correlation analysis by means of which the author establishes qualitative extent of influence of eleven factors on value of net profit of the enterprise of a power complex is submitted.
A. Ievlev
doaj  

Personal protective equipment doffing practices of healthcare workers

open access: yesJournal of Occupational and Environmental Hygiene, 2019
During the doffing of personal protective equipment (PPE), pathogens can be transferred from the PPE to the bodies of healthcare workers (HCWs), putting HCWs and patients at risk of exposure and infection.
Linh T Phan   +6 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

INNOVATION MANAGEMENT OF MAINTENANCE OF MILITARY TECHNIQUE OF THE VIETNAMESE PEOPLE'S ARMY BASED ON NETWORK PLANNING

open access: yesВестник университета, 2019
In the article the application of network planning in organizing the maintenance of military equipment of the Vietnamese People's Army is presented. The orderliness and principle for building network charts have been formed.
M. C. Nguyen, I. Ivanov
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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