Results 151 to 160 of about 49,334 (344)
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
wiley +1 more source
Kevin R Mitchell,1– 3 Alison Bomm,3,4 Barry S Shea,2,3,5 Douglas Shemin,1– 3 George Bayliss1– 3 1Division of Kidney Diseases and Hypertension, Brown Medicine, Providence, RI, USA; 2Alpert Medical School, Brown University, Providence, RI,
Mitchell KR +4 more
doaj
A methodology for developing hospital standards
A methodology for developing hospital standards is comprised of components having characteristics of several hospital systems including the cost accounting system, the budget process, and staffing assessments.
Wise, Leigh Ann
core
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Mass casualty drill in a local hospital
BACKGROUND: In light of the recent political and religious upheaval in Nigeria and several incidents where large numbers of trauma patients were brought to Evangel Hospital, the Consultant staff expressed concern at the lack of organization and ...
Kirschner, Greg, Ardill, William
core +1 more source
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu +14 more
wiley +1 more source
Availability of pediatric services and equipment in emergency departments, United States, 2002-03 [PDF]
"OBJECTIVES: This report presents estimates on the availability of pediatric services, expertise, and supplies for treating pediatric emergencies in U.S. hospitals.
core
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Motivation is the level of a person's willingness to put forth and maintain an effort in support of organizational goals. However, motivation towards task execution is affected by the organization and individual goals.
Eniyew Tegegne +3 more
doaj +1 more source

